Evaluation of wound healing treated with latex derived from rubber trees and Aloe Vera extract in rats
| العنوان: | Evaluation of wound healing treated with latex derived from rubber trees and Aloe Vera extract in rats |
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| المؤلفون: | Marina Pacheco Miguel, Paulo Roberto de Melo Reis, Maisa Helena de Abreu Silva Santos, Lilhian Alves de Araújo, Marcelo Luiz Brandão, Ana Carolina Vicente Araújo |
| المصدر: | Acta Cirúrgica Brasileira v.31 n.9 2016 Acta Cirúrgica Brasileira Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC) instacron:SBDPC Acta Cirurgica Brasileira, Vol 31, Iss 9, Pp 570-577 (2016) Acta Cirurgica Brasileira, Volume: 31, Issue: 9, Pages: 570-577, Published: SEP 2016 |
| بيانات النشر: | FapUNIFESP (SciELO), 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | Male, Pathology, medicine.medical_specialty, RD1-811, Latex, medicine.medical_treatment, Drug Evaluation, Preclinical, Sodium Chloride, 030204 cardiovascular system & hematology, Aloe vera, law.invention, Neovascularization, Random Allocation, 03 medical and health sciences, 0302 clinical medicine, Natural rubber, law, medicine, Animals, Rats, Wistar, Aloe, Saline, Wound Healing, Traditional medicine, biology, Plant Extracts, business.industry, Histology, biology.organism_classification, medicine.disease, Rats, visual_art, visual_art.visual_art_medium, Hevea, 030211 gastroenterology & hepatology, Surgery, Angiogenesis, medicine.symptom, business, Wound healing, Phytotherapy, Foreign body granuloma |
| الوصف: | PURPOSE: To compare the use of latex derivative and Aloe vera extract to wound healing. METHODS: Twenty one rats were randomly divided into three groups and each one had a wound made by incision. The treatment consisted in: derivative of latex (GL), Aloe vera extract (GA) and saline solution (GC). The wound area was measured on the 7th, 14th and 21st days and macroscopic and microscopic evaluation were done. RESULTS: The comparison between the measurements of the wounds presented statistical difference in GC and GA from the 7th day of evaluation and GL from the 14th day. The extent of the wound was significantly smaller by the 7th day in GL. Histologically, in GL, the neovascularization was significant on the 7th, 14th and 21st days. On the 21st day the scar was large and little mature. In GA and GC, the findings were similar on the 7th, 14th and 21st days with a slight better organization of skin and collagen on the 21st in GA. CONCLUSIONS: Statistical analysis did not allow for the definition of the best topical agent. The latex had the highest angiogenesis, but a possible foreign body granuloma. Aloe vera has revealed a healing process adequated temporally in histology. |
| وصف الملف: | text/html |
| تدمد: | 0102-8650 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::741afc9071d19328b73c3a318e305e3fTest https://doi.org/10.1590/s0102-865020160090000001Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....741afc9071d19328b73c3a318e305e3f |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 01028650 |
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