Abobotulinumtoxina injections in shoulder muscles for adult upper limb spasticity: Results from a phase 4 real-world study and a phase 3 open-label trial
| العنوان: | Abobotulinumtoxina injections in shoulder muscles for adult upper limb spasticity: Results from a phase 4 real-world study and a phase 3 open-label trial |
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| المؤلفون: | Thierry Lejeune, Svetlana Khatkova, Lynne Turner-Stokes, Philippe Picaut, Pascal Maisonobe, Jovita Balcaitiene, François Constant Boyer |
| المساهمون: | UCL - SSS/IREC/NMSK - Neuro-musculo-skeletal Lab, UCL - (SLuc) Service de médecine physique et de réadaptation motrice |
| المصدر: | Journal of rehabilitation medicine, Vol. 52, no. 6, p. jrm00068 [1-9] (2020) Journal of Rehabilitation Medicine, Vol 52, Iss 6, p jrm00068 (2020) |
| بيانات النشر: | Medical Journals Sweden AB, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Adult, Male, musculoskeletal diseases, Shoulder, shoulder pain, Acetylcholine Release Inhibitors, Physical Therapy, Sports Therapy and Rehabilitation, RM1-950, Injections, abobotulinumtoxinA, Humans, Botulinum Toxins, Type A, muscle spasticity, shoulder joint, clinical trials, Rehabilitation, General Medicine, Middle Aged, phase III, abobotulinumtoxina, Treatment Outcome, clinical trials, phase iii, Neuromuscular Agents, Muscle Spasticity, Female, observational study, Therapeutics. Pharmacology, human activities |
| الوصف: | Botulinum toxins, such as abobotulinumtoxinA, are used to treat spasticity (muscle overactivity) in arm muscles. Spasticity in shoulder muscles occurs in many patients following a stroke. Shoulder spasticity can be painful and limit limb movement. This paper compares the results from patients who did and those who did not receive abobotulinumtoxinA injections in shoulder muscles (among other arm muscles) in 2 studies. In both studies, the results showed that more patients receiving treatment in shoulder muscles chose pain as a key goal for treatment and had reduced pain following treatment compared with patients not treated in the shoulder. In addition, patients receiving shoulder injections showed further improvement in arm movement compared with those not receiving shoulder injections. Overall, these results suggest that abobotulinumtoxinA treatment in shoulder muscles may improve outcomes for patients with arm spasticity involving the shoulder. |
| اللغة: | English |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71feaf2e77ac620ce24b386372f1dda3Test https://hdl.handle.net/2078.1/230235Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....71feaf2e77ac620ce24b386372f1dda3 |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |