Lipoatrophy among HIV-infected patients is associated with higher levels of depression than lipohypertrophy
| العنوان: | Lipoatrophy among HIV-infected patients is associated with higher levels of depression than lipohypertrophy |
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| المؤلفون: | Mari M. Kitahata, Karina K. Uldall, Paul Ciechanowski, Carl Grunfeld, Robert D. Harrington, Heidi M. Crane |
| المصدر: | HIV Medicine. 9:780-786 |
| بيانات النشر: | Wiley, 2008. |
| سنة النشر: | 2008 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, Cross-sectional study, HIV Infections, Severity of Illness Index, Article, Antiretroviral Therapy, Highly Active, Surveys and Questionnaires, Internal medicine, Severity of illness, Body Image, medicine, Body Fat Distribution, Humans, Pharmacology (medical), Lipoatrophy, Depression (differential diagnoses), Analysis of Variance, Depressive Disorder, business.industry, HIV-Associated Lipodystrophy Syndrome, Health Policy, Lipohypertrophy, Middle Aged, medicine.disease, Cross-Sectional Studies, Infectious Diseases, Endocrinology, Cohort, HIV-1, Female, Body region, Lipodystrophy, business |
| الوصف: | Objectives We sought to determine the association between body morphology abnormalities and depression, examining lipoatrophy and lipohypertrophy separately. Methods An observational cross-sectional study of 250 patients from the University of Washington HIV Cohort was carried out. Patients completed an assessment including measures of depression and body morphology. We used linear regression analysis to examine the association between lipoatrophy or lipohypertrophy and depression. Analysis of variance was used to examine the relationship between mean depression scores and lipoatrophy and lipohypertrophy in 10 body regions. Results Of 250 patients, 76 had lipoatrophy and 128 had lipohypertrophy. Mean depression scores were highest among patients with moderate-to-severe lipoatrophy (16.4), intermediate among those with moderate-to-severe lipohypertrophy (11.7), mild lipohypertrophy (9.9) and mild lipoatrophy (8.5), and lowest among those without body morphology abnormalities (7.7) (P=0.002). After adjustment, mean depression scores for subjects reporting moderate-to-severe lipoatrophy were 9.2 points higher (P |
| تدمد: | 1468-1293 1464-2662 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7032d6b6bb9a69f31af43d3beee3da6bTest https://doi.org/10.1111/j.1468-1293.2008.00631.xTest |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....7032d6b6bb9a69f31af43d3beee3da6b |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14681293 14642662 |
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