| الوصف: |
A newborn female infant presented with an asymptomatic eruption that first began on her fifth day of life. The lesions developed over a 24-hour period, lasted for approximately 3 to 6 weeks before spontaneously resolving, and recurred several days later. When the patient was treated with prednisone by her primary physician for an upper respiratory tract infection, her lesions quickly cleared, only to recur a few days after stopping treatment with the medication. The infant was otherwise healthy with normal growth and development, and no household contacts were experiencing any eruptions or pruritus. Skin examination revealed discrete, annular, erythematous plaques with raised borders and central clearing on the infant’s chest, arms, and neck (Figure, A). At follow-up, it was found that the previous lesions had resolved completely without scarring or residual hyperpigmentation, and new lesions of variable size had developed on her scalp, neck, arms, vulva, and trunk (Figure, B). Results of a complete blood cell count with differential, peripheral smear, complete metabolic panel, and assays for C-reactive protein, antinuclear antibody, anti–double-stranded DNA antibody, anti-SSA, and anti-SSB autoantibodies were all normal. A punch biopsy was performed of a representative lesion of her left medial arm (Figure, C and D). |
