التفاصيل البيبلوغرافية
العنوان:
A phase 3 randomized placebo-controlled trial of tadalafil for Duchenne muscular dystrophy
المؤلفون:
Victor, Ronald G , Sweeney, H. Lee , Finkel, Richard , Mcdonald, Craig M , Byrne, Barry , Eagle, Michelle , Goemans, Nathalie , Vandenborne, Krista , Dubrovsky, Alberto L , Topaloglu, Haluk , Miceli, M. Carrie , Furlong, Pat , Landry, John , Elashoff, Robert , Cox, David , Hoda, Abdel-Hamid , Susan, Apkon , Richard, Barohn , Elena, Belousova , Enrico, Bertini , John, Brandsema , Claudio, Bruno , William, Burnette , Russell, Butterfield , Barry, Byrne , Craig, Campbell , Jose, Carlo , Jong-Hee, Chae , Saleel, Chandratre , Giacomo, Comi , Anne, Connolly , Imelda De Groot , Nicolas, Deconinck , Joseph, Dooley , Alberto, Dubrovsky , Julien, Durigneux , Erika, Finanger , Richard, Finkel , L Matthew Frank , Nathalie, Goemans , Amy, Harper , Ayako, Hattori , Ozlem, Herguner , Susan, Iannaccone , Joanne, Janas , Yuh-Jyh, Jong , Janberd, Kirschner , Hirofumi, Komaki , Nancy, Kuntz , Wang-Tso, Lee , Edward, Leung , Jean, Mah , Katherine, Mathews , Craig, Mcdonald , Eugenio, Mercuri , Hugh, Mcmillan , Wolfgang, Mueller-Felber , Adolfo Lopez de Munain , Akinori, Nakamura , Erik, Niks , Katsuhisa, Ogata , Samuel, Pascual , Pegoraro, Elena , Yann, Pereon , Ben, Renfroe , Ratna Bhavaraju Sanka , Jens, Schallner , Ulrike, Schara , Kathryn, Selby , Isabel Illa Sendra , Laurent, Servais , Edward, Smith , Susan, Sparks , Haluk, Topaloglu , Ron, Victor , Juan Jose Vilchez , Matthew, Wicklund , Ekkehard, Wilichoswki , Brenda, Wong
المساهمون:
L, Servais., Çocuk Sağlığı ve Hastalıkları, Schara, Ulrike (Beitragende*r)
المصدر:
Neurology, vol 89, iss 17
بيانات النشر:
Wolters Kluwer Health, Inc., 2020.
سنة النشر:
2020
مصطلحات موضوعية:
0301 basic medicine , Male , Duchenne muscular dystrophy , Vasodilator Agents , International Cooperation , Left , Medizin , Placebo-controlled study , Walking , Ventricular Function, Left , law.invention , Pulmonary function testing , Tadalafil , Efficacy , 0302 clinical medicine , Randomized controlled trial , law , Heart Rate , Ventricular Function , Muscular Dystrophy , Child , Pediatric , Sciences bio-médicales et agricoles , 3. Good health , Respiratory Function Tests , Treatment Outcome , Area Under Curve , 6.1 Pharmaceuticals , Ambulatory , Cognitive Sciences , Walking -- physiology , Drug , medicine.drug , musculoskeletal diseases , Duchenne/ Becker Muscular Dystrophy , medicine.medical_specialty , Adolescent , Intellectual and Developmental Disabilities (IDD) , Clinical Trials and Supportive Activities , Clinical Sciences , Vasodilator Agents -- therapeutic use , Tadalafil -- therapeutic use , Placebo , Article , Dose-Response Relationship , 03 medical and health sciences , Rare Diseases , Double-Blind Method , Clinical Research , Internal medicine , medicine , Heart Rate -- physiology , Humans , Glucocorticoids , Neurology & Neurosurgery , Dose-Response Relationship, Drug , business.industry , Neurosciences , Evaluation of treatments and therapeutic interventions , medicine.disease , Duchenne , Glucocorticoids -- therapeutic use , Tadalafil DMD Study Group , Brain Disorders , Muscular Dystrophy, Duchenne , 030104 developmental biology , Musculoskeletal , Muscular Dystrophy, Duchenne -- drug therapy -- psychology , Quality of Life , Neurology (clinical) , business , 030217 neurology & neurosurgery , Follow-Up Studies
الوصف:
To conduct a randomized trial to test the primary hypothesis that once-daily tadalafil, administered orally for 48 weeks, lessens the decline in ambulatory ability in boys with Duchenne muscular dystrophy (DMD).
وصف الملف:
application/pdf; Print-Electronic; text/plain; 2 full-text file(s): application/pdf
اللغة:
English
الوصول الحر:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e0e6503a882dfb553f43c58e0475c30Test https://ora.ox.ac.uk/objects/uuid:07acefc6-f3c1-43d6-aaff-dd314f53221cTest
حقوق:
OPEN
رقم الانضمام:
edsair.doi.dedup.....6e0e6503a882dfb553f43c58e0475c30
قاعدة البيانات:
OpenAIRE
