Detection and quantification of beta cells by PET imaging: why clinical implementation has never been closer
| العنوان: | Detection and quantification of beta cells by PET imaging: why clinical implementation has never been closer |
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| المؤلفون: | Miriam Cnop, Sanne A. M. van Lith, Martin Gotthardt, Dick Mul, Henk-Jan Aanstoot, Mijke Buitinga, Frank Martin, Decio L. Eizirik, Maarten Brom, Olle Korsgren, Marti Boss, Olof Eriksson, Tom J.P. Jansen |
| المصدر: | Diabetologia, 61, 12, pp. 2516-2519 Diabetologia, 61 (12 Diabetologia, 61, 2516-2519 |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | 0301 basic medicine, medicine.medical_specialty, Computer science, Endocrinology, Diabetes and Metabolism, PET imaging, 030209 endocrinology & metabolism, Imaging, 03 medical and health sciences, Endocrinology & Metabolism, 0302 clinical medicine, POSITRON-EMISSION-TOMOGRAPHY, All institutes and research themes of the Radboud University Medical Center, Métabolisme, Pancreatic beta Cells, Internal Medicine, medicine, Tumours of the digestive tract Radboud Institute for Molecular Life Sciences [Radboudumc 14], Medical physics, Beta (finance), Diabétologie, Science & Technology, medicine.diagnostic_test, Other Research Radboud Institute for Health Sciences [Radboudumc 0], Pet imaging, Human physiology, Clinical diabetes, Clinical reality, Endocrinologie, Médecine interne, 030104 developmental biology, Positron emission tomography, Islets, Life Sciences & Biomedicine, Preclinical imaging |
| الوصف: | In this issue of Diabetologia, Alavi and Werner (https://doi.org/10.1007/s00125-018-4676-1Test) criticise the attempts to use positron emission tomography (PET) for in vivo imaging of pancreatic beta cells, which they consider as ‘futile’. In support of this strong statement, they point out the limitations of PET imaging, which they believe render beta cell mass impossible to estimate using this method. In our view, the Alavi and Werner presentation of the technical limitations of PET imaging does not reflect the current state of the art, which leads them to questionable conclusions towards the feasibility of beta cell imaging using this approach. Here, we put forward arguments in favour of continuing the development of innovative technologies enabling in vivo imaging of pancreatic beta cells and concisely present the current state of the art regarding putative technical limitations of PET imaging. Indeed, far from being a ‘futile’ effort, we demonstrate that beta cell imaging is now closer than ever to becoming a long-awaited clinical reality. SCOPUS: no.j info:eu-repo/semantics/published |
| وصف الملف: | Print-Electronic; 1 full-text file(s): application/pdf; application/pdf |
| تدمد: | 2516-2519 0012-186X |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d8243a5120d7b6f4dd7b2bac3066feaTest https://hdl.handle.net/2066/197942Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....6d8243a5120d7b6f4dd7b2bac3066fea |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 25162519 0012186X |
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