Transanal total mesorectal excision and low anterior resection syndrome
| العنوان: | Transanal total mesorectal excision and low anterior resection syndrome |
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| المؤلفون: | Mathijs P. Hendriks, J M van Dodewaard-de Jong, J W T Dekker, J.A.G. van der Heijden, Bastiaan R. Klarenbeek, A J G Maaskant-Braat, D J A Sonneveld, T van Voorthuizen, Hein B.A.C. Stockmann, L B J Valkenburg-van Iersel, I.H.J.T. de Hingh, F W H Kloppenberg, G R Vink, Seyed M. Qaderi, F H Beverdam, K Talsma, A H W Schiphorst, J F J Vogelaar, Frans L. G. Erdkamp, H W M U van Grevenstein, W J Vles, Marco B. Polee, Jan B.M.J. Jansen, H H Helgason, P P L O Coene, Geerard L. Beets, E J Th Belt, A U G van Lent, Jan N. M. IJzermans, D D E Zimmerman, M L R Tjin-A-Ton, A J ten Tije, M Berbée, Leonie J. M. Mekenkamp, M P S Sie, Annebeth W. Haringhuizen, Koen C.M.J. Peeters, Maartje Los, A M T van der Velden, N A J B Peters, J W B de Groot, Martijn R. Meijerink, A Schouten van der Velden, A I de Vos, J.H.W. de Wilt, Lieke H.J. Simkens, E G G Verdaasdonk, José A. E. Custers, Peter Nieboer, Rob H.A. Verhoeven, M Vermaas, F Terheggen, P Quarles van Ufford-Mannesse, R Blankenburgh, R Hoekstra, R W M Schrauwen, Dirkje W. Sommeijer, R C Rietbroek, H van Cruijsen, L E A Spierings |
| المساهمون: | Oncology, CCA - Cancer Treatment and Quality of Life, APH - Methodology, APH - Quality of Care, RS: GROW - R3 - Innovative Cancer Diagnostics & Therapy, Epidemiologie, Internal medicine |
| المصدر: | British journal of surgery, 108(8), 991-997. John Wiley and Sons Ltd British Journal of Surgery, 108(8), 991-997. Wiley PLCRC group 2021, ' Transanal total mesorectal excision and low anterior resection syndrome ', British Journal of Surgery, vol. 108, no. 8, pp. 991-997 . https://doi.org/10.1093/bjs/znab056Test British Journal of Surgery, 108, 8, pp. 991-997 British Journal of Surgery, 108, 991-997 British Journal of Surgery, 108(8), 991-997. John Wiley and Sons Ltd |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Male, medicine.medical_specialty, Colorectal cancer, SURGERY, IMPACT, MULTICENTER, 030230 surgery, Logistic regression, 03 medical and health sciences, Tumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14], Postoperative Complications, 0302 clinical medicine, Quality of life, QUALITY-OF-LIFE, Clinical endpoint, Humans, Medicine, Prospective Studies, TATME, Propensity Score, RECTAL-CANCER, Netherlands, Transanal Endoscopic Surgery, PREOPERATIVE RADIOTHERAPY, Low Anterior Resection, INSTRUMENT, Rectal Neoplasms, business.industry, Incidence, Rectum, Syndrome, Middle Aged, medicine.disease, Total mesorectal excision, Surgery, Women's cancers Radboud Institute for Health Sciences [Radboudumc 17], 030220 oncology & carcinogenesis, Propensity score matching, PROCTECTOMY, Female, Laparoscopy, business, CLINICAL-TRIALS, Cohort study |
| الوصف: | Background Bowel dysfunction after rectal cancer surgery is common, with some experiencing low anterior resection syndrome (LARS) is common after rectal cancer surgery. This study examined if transanal total mesorectal excision (TaTME) has a similar risk of LARS and altered quality of life (QoL) as patients who undergo low anterior resection (LAR). Methods Patients who underwent TaTME or traditionally approached total mesorectal excision in a prospective colorectal cancer cohort study (2014–2019) were propensity score matched in a 1 : 1 ratio. LARS and QoL scores were assessed before and after surgery with a primary endpoint of major LARS at 12 months analysed for possible association between factors by logistic regression. Results Of 61 TaTME and 317 LAR patients eligible, 55 from each group were propensity score matched. Higher LARS scores (30.6 versus 25.4, P = 0.010) and more major LARS (65 versus 42 per cent, P = 0.013; OR 2.64, 95 per cent c.i. 1.22 to 5.71) were reported after TaTME. Additionally, QoL score differences (body image, bowel frequency, and embarrassment) were worse in the TaTME group. Conclusions TaTME may be associated with more severe bowel dysfunction than traditional approaches to rectal cancer. |
| اللغة: | English |
| تدمد: | 0007-1323 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c1fcf9a92def7659b2c98d0089aa720Test http://www.scopus.com/inward/record.url?scp=85116172373&partnerID=8YFLogxKTest |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....6c1fcf9a92def7659b2c98d0089aa720 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 00071323 |
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