Quantitative resistance to clubroot infection mediated by transgenerational epigenetic variation in Arabidopsis
| العنوان: | Quantitative resistance to clubroot infection mediated by transgenerational epigenetic variation in Arabidopsis |
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| المؤلفون: | Benjamin Liegard, Mathilde Etcheverry, Mélanie Jubault, Victoire Baillet, Christine Lariagon, Evens Joseph, Maria J. Manzanares-Dauleux, Antoine Gravot, Aurélie Evrard, Vincent Colot, Jocelyne Lemoine |
| المساهمون: | Institut de Génétique, Environnement et Protection des Plantes (IGEPP), Institut National de la Recherche Agronomique (INRA)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-AGROCAMPUS OUEST, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Institut de biologie de l'ENS Paris (UMR 8197/1024) (IBENS), Département de Biologie - ENS Paris, École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), This research was supported by AGROCAMPUS OUEST, INRA and Université de Rennes. Benjamin Liégard was a PhD student co-funded by INRA BAP department and Brittany Region., Institut National de la Recherche Agronomique (INRA)-Université de Rennes (UR)-AGROCAMPUS OUEST, Institut de biologie de l'ENS Paris (IBENS), École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Paris (ENS-PSL), Colot, Vincent, AGROCAMPUS OUEST-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National de la Recherche Agronomique (INRA), École normale supérieure - Paris (ENS Paris)-École normale supérieure - Paris (ENS Paris)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Département de Biologie - ENS Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS) |
| المصدر: | New Phytologist New Phytologist, Wiley, 2019, 222 (1), pp.468-479. ⟨10.1111/nph.15579⟩ New Phytologist, 2019, 222 (1), pp.468-479. ⟨10.1111/nph.15579⟩ The New Phytologist |
| بيانات النشر: | HAL CCSD, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | 0106 biological sciences, 0301 basic medicine, Physiology, Inheritance Patterns, Arabidopsis, Plant Science, methylome, Plasmodiophorida, [SDV.BBM.BM] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, 01 natural sciences, Epigenesis, Genetic, [SDV.GEN.GPL] Life Sciences [q-bio]/Genetics/Plants genetics, [SDV.BV] Life Sciences [q-bio]/Vegetal Biology, Disease Resistance, Genetics, [SDV.BIBS] Life Sciences [q-bio]/Quantitative Methods [q-bio.QM], Full Paper, [SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE], Temperature, food and beverages, Full Papers, [SDV.BIBS]Life Sciences [q-bio]/Quantitative Methods [q-bio.QM], Phenotype, Plasmodiophora brassicae, DNA methylation, [SDV.BBM.GTP] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], quantitative resistance, Quantitative Trait Loci, clubroot, Biology, Plant disease resistance, Quantitative trait locus, Clubroot, [SDV.GEN.GPL]Life Sciences [q-bio]/Genetics/Plants genetics, 03 medical and health sciences, [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], medicine, [SDV.BID.EVO] Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE], [SDV.BV]Life Sciences [q-bio]/Vegetal Biology, transgenerational, Epigenetics, Allele, Gene, Plant Diseases, [SDV.GEN.GPO]Life Sciences [q-bio]/Genetics/Populations and Evolution [q-bio.PE], Base Sequence, epigenetics, Research, Genetic Variation, epigenet- ics, [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, DNA Methylation, medicine.disease, biology.organism_classification, EpiRIL, 030104 developmental biology, Mutation, [SDV.GEN.GPO] Life Sciences [q-bio]/Genetics/Populations and Evolution [q-bio.PE], 010606 plant biology & botany |
| الوصف: | International audience; Quantitative disease resistance, often influenced by environmental factors, is thought to be the result of DNA sequence variants segregating at multiple loci. However, heritable differences in DNA methylation, so-called transgenerational epigenetic variants, also could contribute to quantitative traits. Here, we tested this possibility using the well-characterized quantitative resistance of Arabidopsis to clubroot, a Brassica major disease caused by Plasmodiophora brassicae. For that, we used the epigenetic recombinant inbred lines (epiRIL) derived from the cross ddm1-2 9 Col-0, which show extensive epigenetic variation but limited DNA sequence variation. Quantitative loci under epigenetic control (QTL epi) mapping was carried out on 123 epiRIL infected with P. brassicae and using various disease-related traits. EpiRIL displayed a wide range of continuous phenotypic responses. Twenty QTL epi were detected across the five chromosomes, with a bona fide epigenetic origin for 16 of them. The effect of five QTL epi was dependent on temperature conditions. Six QTL epi co-localized with previously identified clubroot resistance genes and QTL in Arabidopsis. Co-localization of clubroot resistance QTL epi with previously detected DNA-based QTL reveals a complex model in which a combination of allelic and epiallelic variations interacts with the environment to lead to variation in clubroot quantitative resistance. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 0028-646X 1469-8137 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bce50617e04394d89a4544a3a65c898Test https://hal.archives-ouvertes.fr/hal-02414174Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....6bce50617e04394d89a4544a3a65c898 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 0028646X 14698137 |
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