RESUME : A flexible class of multi-parameter qMRI protocols

التفاصيل البيبلوغرافية
العنوان: RESUME : A flexible class of multi-parameter qMRI protocols
المؤلفون: Sirio Cocozza, Laura Cella, Serena Monti, Giuseppe Palma, Giuseppe Pontillo, Camilla Russo
المصدر: Physica medica (Testo stamp.) 88 (2021): 23–36. doi:10.1016/j.ejmp.2021.04.005
info:cnr-pdr/source/autori:Monti, Serena; Pontillo, Giuseppe; Russo, Camilla; Cella, Laura; Cocozza, Sirio; Palma, Giuseppe/titolo:RESUMEN<%2Fsup>: A flexible class of multi-parameter qMRI protocols/doi:10.1016%2Fj.ejmp.2021.04.005/rivista:Physica medica (Testo stamp.)/anno:2021/pagina_da:23/pagina_a:36/intervallo_pagine:23–36/volume:88
بيانات النشر: Elsevier BV, 2021.
سنة النشر: 2021
مصطلحات موضوعية: Relaxometry, Sequence, Computer science, Pipeline (computing), QSM, Biophysics, General Physics and Astronomy, Relaxation (iterative method), Neuroimaging, Quantitative susceptibility mapping, Quantitative MRI, General Medicine, computer.software_genre, 030218 nuclear medicine & medical imaging, Free induction decay, 03 medical and health sciences, 0302 clinical medicine, Voxel, 030220 oncology & carcinogenesis, Range (statistics), Radiology, Nuclear Medicine and imaging, computer, Algorithm
الوصف: Purpose To introduce a class of fast 3D quantitative MRI (qMRI) schemes (RESUMEN, for N = 1 , … , 4 ) that allow for a thorough characterization of microstructural properties of brain tissues. Methods An arbitrary multi-echo GRE acquisition optimized for quantitative susceptibility mapping (QSM) is complemented with an appropriate low flip-angle GRE sequence drawn from four possible choices. The acquired signals are processed to analytically derive the longitudinal relaxation ( R 1 ) and free induction decay ( R 2 ∗ ) rates, as well as the proton density (PD) and QSM. A comprehensive modeling of the excitation and B 1 - profiles and of the RF-spoiling is included in the acquisition and processing pipeline. Results The RESUMEN maps appear homogeneous throughout the field-of-view and exhibit comparable values and high SNR across the considered range of N values. Conclusions The introduced schemes represent a class of robust and flexible strategies to derive a thorough and fast qMRI study, suitable for a whole-brain acquisition with isotropic voxel resolution of 700 μ m in less than 15 min.
تدمد: 1120-1797
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b72653e59c10412afffea6361801b53Test
https://doi.org/10.1016/j.ejmp.2021.04.005Test
حقوق: OPEN
رقم الانضمام: edsair.doi.dedup.....6b72653e59c10412afffea6361801b53
قاعدة البيانات: OpenAIRE