RESUME : A flexible class of multi-parameter qMRI protocols
العنوان: | RESUME : A flexible class of multi-parameter qMRI protocols |
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المؤلفون: | Sirio Cocozza, Laura Cella, Serena Monti, Giuseppe Palma, Giuseppe Pontillo, Camilla Russo |
المصدر: | Physica medica (Testo stamp.) 88 (2021): 23–36. doi:10.1016/j.ejmp.2021.04.005 info:cnr-pdr/source/autori:Monti, Serena; Pontillo, Giuseppe; Russo, Camilla; Cella, Laura; Cocozza, Sirio; Palma, Giuseppe/titolo:RESUMEN<%2Fsup>: A flexible class of multi-parameter qMRI protocols/doi:10.1016%2Fj.ejmp.2021.04.005/rivista:Physica medica (Testo stamp.)/anno:2021/pagina_da:23/pagina_a:36/intervallo_pagine:23–36/volume:88 |
بيانات النشر: | Elsevier BV, 2021. |
سنة النشر: | 2021 |
مصطلحات موضوعية: | Relaxometry, Sequence, Computer science, Pipeline (computing), QSM, Biophysics, General Physics and Astronomy, Relaxation (iterative method), Neuroimaging, Quantitative susceptibility mapping, Quantitative MRI, General Medicine, computer.software_genre, 030218 nuclear medicine & medical imaging, Free induction decay, 03 medical and health sciences, 0302 clinical medicine, Voxel, 030220 oncology & carcinogenesis, Range (statistics), Radiology, Nuclear Medicine and imaging, computer, Algorithm |
الوصف: | Purpose To introduce a class of fast 3D quantitative MRI (qMRI) schemes (RESUMEN, for N = 1 , … , 4 ) that allow for a thorough characterization of microstructural properties of brain tissues. Methods An arbitrary multi-echo GRE acquisition optimized for quantitative susceptibility mapping (QSM) is complemented with an appropriate low flip-angle GRE sequence drawn from four possible choices. The acquired signals are processed to analytically derive the longitudinal relaxation ( R 1 ) and free induction decay ( R 2 ∗ ) rates, as well as the proton density (PD) and QSM. A comprehensive modeling of the excitation and B 1 - profiles and of the RF-spoiling is included in the acquisition and processing pipeline. Results The RESUMEN maps appear homogeneous throughout the field-of-view and exhibit comparable values and high SNR across the considered range of N values. Conclusions The introduced schemes represent a class of robust and flexible strategies to derive a thorough and fast qMRI study, suitable for a whole-brain acquisition with isotropic voxel resolution of 700 μ m in less than 15 min. |
تدمد: | 1120-1797 |
الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b72653e59c10412afffea6361801b53Test https://doi.org/10.1016/j.ejmp.2021.04.005Test |
حقوق: | OPEN |
رقم الانضمام: | edsair.doi.dedup.....6b72653e59c10412afffea6361801b53 |
قاعدة البيانات: | OpenAIRE |
تدمد: | 11201797 |
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