MRI versus CT and PET/CT in the Preoperative Assessment of Hodgkin and Non-Hodgkin Lymphomas
| العنوان: | MRI versus CT and PET/CT in the Preoperative Assessment of Hodgkin and Non-Hodgkin Lymphomas |
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| المؤلفون: | Carlo de Felice, Arianna Cleri, Francesca Maccioni, Luigi Petrucci, Lucia Manganaro, Mariangela Lopez, Carlo Catalano, Alessandro Calabrese, Sara Cardaccio, Gabriela Capriotti, Alessandro Pulsoni |
| المصدر: | Hemato, Vol 2, Iss 41, Pp 635-644 (2021) Hemato Volume 2 Issue 4 Pages 41-644 |
| بيانات النشر: | MDPI AG, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | PET-CT, business.industry, PET/CT, non-Hodgkin lymphoma, Lymphoma staging, Diagnostic accuracy, Total body, Gold standard (test), staging, medicine.disease, Lymphoma, medicine, diffusion weighted imaging, Medicine, business, Nuclear medicine, Reference standards, Hodgkin lymphoma, Diffusion MRI, MRI, CT |
| الوصف: | (1) Background: The purpose of this study is to retrospectively compare CT, MRI, and PET/CT in detecting lymphadenopathies and extra-nodal lesions in lymphoma and in disease staging. (2) Methods: Inclusion criteria were the availability of TB (Total Body) CT and/or PET/CT performed before treatment MRI performed no later than 2 weeks after TBCT histological confirmation of lymphoma clinical-diagnostic follow-up. Using these criteria, we included 64/353 patients with TBCT and MRI performed at our hospital 20/64 had PET/CT performed in other hospitals. Histology and follow-up were gold standard. (3) Results: The sensitivity, specificity, and accuracy in lymph nodes detection was 84.5%, 94.4%, and 91% for CT and 95%, 98.9%, and 95.6% for MRI. High agreement was observed between CT and MRI regarding the number and size of positive lymph nodes and for disease staging. MRI identified eight more extra-nodal lesions than CT. In the subgroup of 20 patients, PET/CT did not show a significant superiority in sensitivity, specificity, accuracy, and staging ability than CT and MRI. (4) Conclusions: Our study demonstrates a mild superiority of MRI over CT in lymphoma staging. Although PET/CT remains the reference standard, MRI demonstrated a similar diagnostic accuracy, with the added value of being radiation-free. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2673-6357 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::671abbb5516dc30124b19fa444988b40Test https://www.mdpi.com/2673-6357/2/4/41Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....671abbb5516dc30124b19fa444988b40 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 26736357 |
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