Carbohydrate based meningococcal vaccines: past and present overview
| العنوان: | Carbohydrate based meningococcal vaccines: past and present overview |
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| المؤلفون: | Maria Romano, Roberto Adamo, Francesca Micoli, Francesco Berti |
| المصدر: | Glycoconjugate Journal |
| بيانات النشر: | Springer Science and Business Media LLC, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Glycoconjugate, Mini Review, Meningococcal Infections, Meningococcal Vaccines, Meningococcal vaccine, Neisseria meningitidis, medicine.disease_cause, Biochemistry, Microbiology, 03 medical and health sciences, 0302 clinical medicine, Humans, Medicine, 030212 general & internal medicine, Molecular Biology, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Vaccines, Conjugate, business.industry, Cell Biology, chemistry, business, Glycoconjugates |
| الوصف: | Neisseria meningitidis is a major cause of bacterial meningitidis worldwide. Children less than five years and adolescents are particularly affected. Nearly all invasive strains are surrounded by a polysaccharide capsule, based on which, 12 N. meningitidis serogroups are differentiated. Six of them, A, B, C, W, X, and Y, cause the vast majority of infections in humans. Mono- and multi-valent carbohydrate-based vaccines against meningococcal infections have been licensed or are currently in clinical development. In this mini-review, an overview of the past and present approaches for producing meningococcal glycoconjugate vaccines is provided. |
| تدمد: | 1573-4986 0282-0080 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::671869a84a29ded4c4ae55d8fa958862Test https://doi.org/10.1007/s10719-021-09990-yTest |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....671869a84a29ded4c4ae55d8fa958862 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15734986 02820080 |
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