Heterocyclic Compounds from the Mushroom Albatrellus confluens and Their Inhibitions against Lipopolysaccharides-Induced B Lymphocyte Cell Proliferation
| العنوان: | Heterocyclic Compounds from the Mushroom Albatrellus confluens and Their Inhibitions against Lipopolysaccharides-Induced B Lymphocyte Cell Proliferation |
|---|---|
| المؤلفون: | Bin Wu, He-Ping Chen, Jianping Zuo, Zheng-Hui Li, Ji-Kai Liu, Shuai-Bing Zhang, Ying Huang, Shanyong Li, Zhen-Zhu Zhao, Tao Feng, Xian Wang, Shijun He |
| المصدر: | The Journal of Organic Chemistry. 83:10158-10165 |
| بيانات النشر: | American Chemical Society (ACS), 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Lipopolysaccharides, Stereochemistry, Lymphocyte, Stereoisomerism, 010402 general chemistry, 01 natural sciences, Mice, Heterocyclic Compounds, medicine, Albatrellus confluens, Ic50 values, Animals, Cell Proliferation, B-Lymphocytes, Mice, Inbred BALB C, Mushroom, biology, 010405 organic chemistry, Chemistry, Cell growth, Basidiomycota, Organic Chemistry, Total synthesis, biology.organism_classification, 0104 chemical sciences, medicine.anatomical_structure, Female |
| الوصف: | Eight hetereocyclic compounds conflamides B–I with an unprecedented skeleton and their precursor conflamide A were isolated from the mushroom Albatrellus confluens. Their structures and absolute configurations were determined by use of NMR studies, total synthesis, and calculated ECD spectra. Conflamides D and E were found to exhibit potent inhibition against LPS-induced B lymphocyte cell proliferation with IC50 values 1.48 and 5.71 μM, respectively. |
| تدمد: | 1520-6904 0022-3263 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::667d1d5fe2b6f4c528cc641eb45ef196Test https://doi.org/10.1021/acs.joc.8b01420Test |
| رقم الانضمام: | edsair.doi.dedup.....667d1d5fe2b6f4c528cc641eb45ef196 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15206904 00223263 |
|---|