Platelet to lymphocyte ratio predicting 6-month primary patency of drug-coated balloon for femoropopliteal disease
| العنوان: | Platelet to lymphocyte ratio predicting 6-month primary patency of drug-coated balloon for femoropopliteal disease |
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| المؤلفون: | Yanhua Zhen, Zhihui Chang, Zhaoyu Liu, Jiahe Zheng |
| المصدر: | BMC Cardiovascular Disorders, Vol 20, Iss 1, Pp 1-6 (2020) BMC Cardiovascular Disorders |
| بيانات النشر: | BMC, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Male, lcsh:Diseases of the circulatory (Cardiovascular) system, Time Factors, Lymphocyte, Primary patency, 030204 cardiovascular system & hematology, Balloon, Systemic inflammation, Gastroenterology, Group B, 030218 nuclear medicine & medical imaging, 0302 clinical medicine, Coated Materials, Biocompatible, Risk Factors, Platelet, Popliteal Artery, Lymphocytes, Middle Aged, Cardiac surgery, Femoral Artery, medicine.anatomical_structure, Treatment Outcome, Female, medicine.symptom, Cardiology and Cardiovascular Medicine, Research Article, Blood Platelets, medicine.medical_specialty, Subgroup analysis, Risk Assessment, 03 medical and health sciences, Peripheral Arterial Disease, Internal medicine, medicine, Humans, Lymphocyte Count, Vascular Patency, Angiology, Aged, Retrospective Studies, business.industry, Platelet Count, Cardiovascular Agents, Femoropopliteal disease, body regions, lcsh:RC666-701, Drug-coated balloon, business, Angioplasty, Balloon |
| الوصف: | Background Inflammatory reaction is an essential factor in the occurrence, development and prognosis of femoropopliteal disease (FPD). The ratio of platelets to lymphocytes (PLR) is a new indicator reflecting platelet aggregation and burden of systemic inflammation. Our study is to explore the association between preoperative platelet-to-lymphocyte ratio (pre-PLR) and 6-month primary patency (PP) after drug-coated balloon (DCB) in FPD. Methods There were 70 patients who underwent DCB for FPD contained in the study. According to 6-month PP, patients were divided into group A (PP ≥6 months, n = 54) and group B (PP n = 16). Logistic regression analysis was used to identify potential predictors for 6-month PP after DCB in FPD. A receiver operating characteristic (ROC) curve analysis was used to identify the cut-off value of pre-PLR to predict 6-month PP. Results Logistic regression analysis showed that pre-PLR (OR: 1.008, 95% CI: 1.001–1.016, P = 0.031) and lesion length > 10 cm (OR: 4.305, 95% CI: 1.061–17.465, P = 0.041) were independently predictive for 6-month PP. The cutoff value of pre-PLR obtained from the ROC analysis was 127.35 to determine 6-month PP with the area of 0.839. Subgroup analysis was conducted based on the cutoff value of pre-PLR. The 6-month PP in the group of pre-PLR p Conclusions The present study indicated that an elevated pre-PLR was an effective additional indicator for predicting early PP in FPD after DCB. |
| اللغة: | English |
| تدمد: | 1471-2261 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64b733edc730d32161740dae0f76cd34Test https://doaj.org/article/db7950e320b94beabe483894c66ea25eTest |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....64b733edc730d32161740dae0f76cd34 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14712261 |
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