The intersectional role of social stress in fracture risk: results from the Women’s Health Initiative
| العنوان: | The intersectional role of social stress in fracture risk: results from the Women’s Health Initiative |
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| المؤلفون: | Jean Wactawski-Wende, Zhao Chen, Aladdin H. Shadyab, Hilary A. Tindle, David O. Garcia, Chengcheng Hu, Yann C. Klimentidis, Shawna Follis, Melissa Flores, Jennifer W. Bea, Lindsay N. Kohler |
| المصدر: | Journal of Epidemiology and Community Health. 75:1208-1214 |
| بيانات النشر: | BMJ, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Epidemiology, Population, 030209 endocrinology & metabolism, Social epidemiology, 03 medical and health sciences, Social support, 0302 clinical medicine, Risk Factors, medicine, Humans, 030212 general & internal medicine, education, Aged, Social stress, education.field_of_study, Hip fracture, Hip Fractures, business.industry, Incidence, Women's Health Initiative, Incidence (epidemiology), Public Health, Environmental and Occupational Health, Social environment, Middle Aged, medicine.disease, Postmenopause, Women's Health, Female, business, Stress, Psychological, Demography |
| الوصف: | BackgroundThe biological consequences of stress from the social environment pattern health outcomes. This study investigated whether social stress is prospectively associated with fracture incidence among racially and ethnically diverse, postmenopausal women.MethodsData from 160 709 postmenopausal women in the Women’s Health Initiative was analysed using Cox proportional hazards regression models to examine prospective associations of social stress with time to total and hip fracture incidence. Self-reported questionnaires measuring social strain, social functioning and social support were used to assess social stress.ResultsAge and race/ethnicity modified associations between social stress and total and hip fractures. HRs for the associations between higher social support (indicating lower social stress) and total fractures among those age 50–59 years were 0.92 (95% CI: 0.90 to 0.94); HR=0.94 (95% CI: 0.93 to 0.95) for those age 60–69 years and HR=0.96 (95% CI: 0.95 to 0.98) for those age 70–79 years. Higher social strain was associated with greater hip fracture incidence among Native American women (HR=1.84, 95% CI: 1.10 to 3.10), Asian women (HR=1.37, 95% CI: 1.01 to 1.86) and white women (HR=1.04, 95% CI: 1.01 to 1.08).ConclusionIdentifying population patterns of fracture incidence as biological expressions of social environments reveals how race/ethnic specific social environmental factors influence disparities in fractures. |
| تدمد: | 1470-2738 0143-005X |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60715d4b0ed8d956831186786d4dffe0Test https://doi.org/10.1136/jech-2020-216354Test |
| رقم الانضمام: | edsair.doi.dedup.....60715d4b0ed8d956831186786d4dffe0 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14702738 0143005X |
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