Aim To evaluate the prognosis of diabetic gastroparesis. Methods Eighty-six patients with diabetes had measurements of gastric emptying of a mixed meal using a dual isotope test of solid and liquid meal components, mean blood glucose levels, HbA1c, upper gastrointestinal symptoms and autonomic nerve function performed in 1984–1989. These patients were followed up in 2011, after a mean period of ~25 years. Results Of the 86 patients, gastric emptying of solid (the percentage remaining in the stomach at 100 min) was delayed in 35 (41%), and of liquid (the time taken for 50% of the liquid to empty) was delayed in 38 (44%). In 2011, 53 patients were known to be alive, 29 had died and four were lost to follow-up. In those who had died, both age at baseline (P