An association of human T-cell lymphotropie virus type I infection with vascular dementia
| العنوان: | An association of human T-cell lymphotropie virus type I infection with vascular dementia |
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| المؤلفون: | Jun Ichi Kira, M. Okayama, Takeshi Hamada, Yuji Kawano, Kenji Yamasaki |
| المصدر: | Acta Neurologica Scandinavica. 96:305-309 |
| بيانات النشر: | Hindawi Limited, 2009. |
| سنة النشر: | 2009 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, Pathology, Endemic Diseases, viruses, Gastroenterology, Central nervous system disease, Degenerative disease, Japan, Alzheimer Disease, Risk Factors, Internal medicine, mental disorders, Epidemiology, medicine, Humans, Dementia, Risk factor, Vascular dementia, Aged, Aged, 80 and over, Neurologic Examination, Human T-lymphotropic virus 1, Virulence, Cerebral infarction, Vascular disease, business.industry, Dementia, Vascular, General Medicine, Middle Aged, medicine.disease, HTLV-I Infections, Neurology, Female, Neurology (clinical), Tomography, X-Ray Computed, business |
| الوصف: | Subjects ranging in age from 50 to 89 years old, either with or without dementia were studied by both ELISA for anti-human T-cell lymphotropic virus type I (HTLV-I) gag 100-130 antibody and by cranial CT in order to clarify the relationship between HTLV-I infection and dementia. The frequency of anti-HTLV-I antibody was found to be significantly higher in the patients with dementia (24/130, 18.5%) than in those without dementia (11/139, 7.9%) (P=0.0169). Among the various types of dementia, HTLV-I seropositivity was found to be significantly associated with vascular dementia (11/48, 23%) (P= 0.0087), but not with Alzheimer type dementia. In addition, HTLV-I seropositivity was also associated with Babinski sign, and the severity of cerebral infarction, ventricular dilatation and periventricular lucency on CT. The presence of HTLV-I therefore appears to be one of the risk factors for vascular dementia in HTLV-I endemic areas. |
| تدمد: | 1600-0404 0001-6314 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dc24241461bece45bc9e8a4fab6cb00Test https://doi.org/10.1111/j.1600-0404.1997.tb00288.xTest |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....5dc24241461bece45bc9e8a4fab6cb00 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 16000404 00016314 |
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