Oat bran, but not its isolated bioactiveβ-glucans or polyphenols, have a bifidogenic effect in anin vitrofermentation model of the gut microbiota
| العنوان: | Oat bran, but not its isolated bioactiveβ-glucans or polyphenols, have a bifidogenic effect in anin vitrofermentation model of the gut microbiota |
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| المؤلفون: | Manuel Y. Schär, Gulten Soycan, Angelika Kristek, Gunter G. C. Kuhnle, Ondrej Kosik, Jeremy P. E. Spencer, Patrizia Heuer, Sarah N. S. Alsharif, Gemma E. Walton, Maria Wiese |
| المصدر: | Kristek, A, Wiese, M, Heuer, P, Kosik, O, Schär, M Y, Soycan, G, Alsharif, S, Kuhnle, G G C, Walton, G & Spencer, J P E 2019, ' Oat bran, but not its isolated bioactive β-glucans or polyphenols, have a bifidogenic effect in an in vitro fermentation model of the gut microbiota ', British Journal of Nutrition, vol. 121, no. 5, pp. 549-559 . https://doi.org/10.1017/S0007114518003501Test |
| بيانات النشر: | Cambridge University Press (CUP), 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | 0301 basic medicine, beta-Glucans, Avena, medicine.medical_treatment, Medicine (miscellaneous), Gut microbiota, Bifidogenic effects, Gut flora, Bifidogenic effects, Oats, beta-Glucan, Feces, 03 medical and health sciences, β-Glucan, Proteobacteria, medicine, Humans, Food science, 16S rRNA gene sequencing, Acetic Acid, Bifidobacterium, Whole Grains, 030109 nutrition & dietetics, Nutrition and Dietetics, biology, Bacteroidetes, Chemistry, Prebiotic, food and beverages, Polyphenols, SCFA, biology.organism_classification, Enterobacteriaceae, Gastrointestinal Microbiome, Prebiotics, 030104 developmental biology, Polyphenol, Fermentation, Whole food, Propionates |
| الوصف: | Wholegrain oats are known to modulate the human gut microbiota and have prebiotic properties (increase the growth of some health-promoting bacterial genera within the colon). Research to date mainly attributes these effects to the fibre content; however, oat is also a rich dietary source of polyphenols, which may contribute to the positive modulation of gut microbiota.In vitroanaerobic batch-culture experiments were performed over 24 h to evaluate the impact of two different doses (1 and 3 % (w/v)) of oat bran, matched concentrations ofβ-glucan extract or polyphenol mix, on the human faecal microbiota composition using 16S RNA gene sequencing and SCFA analysis. Supplementation with oats increased the abundance of Proteobacteria (PPsd27)v. 28 (sd5) mm;PBifidobacteriumunassigned at 10 h andBifidobacterium adolescentis(Pβ-glucan treatment induced an increase in the phylum Bacteroidetes at 24 h, it explains the Bacteriodetes effects of oats as a food matrix. The polyphenol mix induced an increase in Enterobacteriaceae family at 24 h. In conclusion, in this study, we found that oats increased bifidobacteria, acetic acid and propionic acid, and this is mediated by the synergy of all oat compounds within the complex food matrix, rather than its main bioactiveβ-glucan or polyphenols. Thus, oats as a whole food led to the greatest impact on the microbiota. |
| وصف الملف: | application/pdf |
| تدمد: | 1475-2662 0007-1145 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c692f687f7cb2fbcbf326289bb2e7feTest https://doi.org/10.1017/s0007114518003501Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....5c692f687f7cb2fbcbf326289bb2e7fe |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14752662 00071145 |
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