التفاصيل البيبلوغرافية
العنوان:
Evaluation of the relationship between glycated hemoglobin A1c and mean glucose levels derived from the professional continuous flash glucose monitoring system
المؤلفون:
Tsugumichi Saito , Claire C. Bastie , Eijiro Yamada , Shuichi Okada , Hiroki Oda , Atsushi Ozawa , Aya Osaki , Ryota Uehara , Yuko Kasai , Masanobu Yamada , Yasuyo Nakajima , Yoko Shimoda , Ryo Shibusawa
المصدر:
Endocrine journal . 67(5)
سنة النشر:
2020
مصطلحات موضوعية:
Adult , Blood Glucose , Male , medicine.medical_specialty , endocrine system diseases , Glycated hemoglobin-A1c , Endocrinology, Diabetes and Metabolism , Urology , 030209 endocrinology & metabolism , Type 2 diabetes , 03 medical and health sciences , chemistry.chemical_compound , Hba1c level , 0302 clinical medicine , Endocrinology , Diabetes mellitus , medicine , Humans , Hypoglycemic Agents , Insulin , Aged , Glycated Hemoglobin , Continuous glucose monitoring , business.industry , Blood Glucose Self-Monitoring , nutritional and metabolic diseases , Data interpretation , Monitoring system , Middle Aged , medicine.disease , Diabetes Mellitus, Type 1 , chemistry , Diabetes Mellitus, Type 2 , 030220 oncology & carcinogenesis , Female , Glycated hemoglobin , business
الوصف:
Previously, we reported that short-term continuous glucose monitoring (CGM) with the professional iPro2© CGM device is a good clinical indicator of glycated hemoglobin (HbA1c) levels. However, there was no significant correlation between CGM and HbA1c levels when HbA1c levels were >8.0%. To further investigate this issue, we performed a similar study using the FreeStyle Libre Pro©, a newer device that does not require glucose calibration and allows patients to be examined for up to 14 days. Fifty-nine patients (68% women, 32% men) were examined. Twenty-eight and 31 patients presented with type 1 and type 2 diabetes, respectively. Clinically assessed HbA1c levels were compared to blood glucose levels determined by the FreeStyle Libre Pro© for up to 14 days (10.7 ± 3.7 days). We found a significant correlation between HbA1c and CGM levels even when HbA1c levels were >8.0%. Additionally, the correlation between HbA1c and average glucose was identified with the modern CGM and was found to deviate substantially from the new suggested formula. More importantly, we found a more robust correlation between HbA1c and CGM levels in patients with type 2 diabetes. Overestimation or underestimation of blood glucose levels through CGM might increase the risks of inappropriate clinical treatment of diabetes patients. Our results indicate the need for proper CGM data interpretation individualized for each patient to better assist the determination of customized treatments for patients.
تدمد:
1348-4540
الوصول الحر:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b55111fb295e5805fe21fb9cdf063afTest https://pubmed.ncbi.nlm.nih.gov/32023560Test
حقوق:
OPEN
رقم الانضمام:
edsair.doi.dedup.....5b55111fb295e5805fe21fb9cdf063af
قاعدة البيانات:
OpenAIRE
