Respiratory impedance response to continuous negative airway pressure in awake controls and OSAS
| العنوان: | Respiratory impedance response to continuous negative airway pressure in awake controls and OSAS |
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| المؤلفون: | Frédéric Lofaso, Alain Harf, Lorino Am, Hubert Lorino, E Dahan |
| المصدر: | European Respiratory Journal. 17:71-78 |
| بيانات النشر: | European Respiratory Society (ERS), 2001. |
| سنة النشر: | 2001 |
| مصطلحات موضوعية: | Adult, Male, Pulmonary and Respiratory Medicine, Ventilators, Negative-Pressure, Forced Oscillation Technique, Linear regression, medicine, Humans, Respiratory system, Aged, Sleep Apnea, Obstructive, Sleep disorder, Receiver operating characteristic, business.industry, Airway Resistance, Respiratory disease, Middle Aged, medicine.disease, respiratory tract diseases, Inertance, ROC Curve, Anesthesia, Female, Pulmonary Ventilation, business, Airway |
| الوصف: | The aim of the study was to determine whether the response of respiratory impedance (Zrs) to decreasing levels of continuous negative airway pressure (CNAP) during wakefulness, differs in controls and subjects with obstructive sleep apnoea syndrome (OSAS).Zrswas measured by the forced oscillation technique (4–32 Hz) in 15 controls and 21 patients with OSAS (apnoea/hypopnoea index >20 per sleep hour) with normal lung function, in the basal state and with application of decreasing CNAP of −5, −10, and −15 hPa. Respiratory resistance was extrapolated to 0 Hz (R0) and estimated at 16 Hz (R16) by linear regression analysis of respiratory resistive impedanceversusfrequency. Respiratory elastance (Ers) and inertance (Irs) were estimated by multilinear regression analysis of respiratory reactanceversusfrequency, and resonance frequency (RF) was determined as RF=(1/2π)(Ers/Irs)0.5.In both groups,R0,R16,Ersand RF significantly increased as the CNAP level decreased (pR0,Ers, and RF increased significantly more in OSAS than in controls (pThe results of the present study suggest that the response of respiratory impedance to decreasing continuous negative airway pressure levels, might allow detection of obstructive sleep apnoea syndrome in subjects with normal lung function. |
| تدمد: | 1399-3003 0903-1936 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ad64f94e7b16f1a9cee4de79a3184efTest https://doi.org/10.1183/09031936.01.17100710Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....5ad64f94e7b16f1a9cee4de79a3184ef |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 13993003 09031936 |
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