The level of vascular endothelial cell growth factor, nitric oxide, and endothelin-1 was correlated with ovarian volume or antral follicle counts: A potential predictor of pregnancy outcome in IVF
| العنوان: | The level of vascular endothelial cell growth factor, nitric oxide, and endothelin-1 was correlated with ovarian volume or antral follicle counts: A potential predictor of pregnancy outcome in IVF |
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| المؤلفون: | Zhuang Liu, Li Chen, M Zhao, C. Chang, Qixin Chen |
| المصدر: | Growth Factors. 28:299-305 |
| بيانات النشر: | Informa UK Limited, 2010. |
| سنة النشر: | 2010 |
| مصطلحات موضوعية: | Adult, Vascular Endothelial Growth Factor A, endocrine system, medicine.medical_specialty, Pregnancy Rate, medicine.medical_treatment, Clinical Biochemistry, Cell Count, Fertilization in Vitro, Nitric Oxide, Nitric oxide, chemistry.chemical_compound, Endocrinology, Ovarian Follicle, Pregnancy, Internal medicine, medicine, Humans, In vitro fertilisation, Endothelin-1, business.industry, Organ Size, Cell Biology, Antral follicle, medicine.disease, Endothelin 1, Follicular fluid, Follicular Fluid, Pregnancy rate, chemistry, Female, business, Endothelial Cell Growth Factor |
| الوصف: | The objective of this study was to investigate the correlation between the concentrations of vascular endothelial cell growth factor (VEGF), nitric oxide (NO), or endothelin-1 (ET-1) in follicular fluid with antral follicle counts (AFCs) or ovarian volume in order to predict the outcome of in vitro fertilization (IVF). One hundred and thirty-one patients were enrolled in this study, and the pregnancy rate was 37.4%. The concentration of VEGF or NO was significantly increased, while the concentration of ET-1 in follicular fluid was decreased in the group who became pregnant (P#x00A0;lt;#x00A0;0.05). The ovarian volume or AFC was significantly higher in groups that became pregnant (P#x00A0;lt;#x00A0;0.05). In addition, the ovarian volume or AFC was positively correlated with the concentration of VEGF or NO and negatively correlated with the concentration of ET-1 in follicular fluid. Our data suggest that these correlations may be associated with the successful pregnancies through IVF. |
| تدمد: | 1029-2292 0897-7194 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a3284e749ef9909d64bc812efdfdcc3Test https://doi.org/10.3109/08977191003766866Test |
| رقم الانضمام: | edsair.doi.dedup.....5a3284e749ef9909d64bc812efdfdcc3 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 10292292 08977194 |
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