Secondary Particle Interactions in a Compton Camera Designed for in vivo Range Verification of Proton Therapy
| العنوان: | Secondary Particle Interactions in a Compton Camera Designed for in vivo Range Verification of Proton Therapy |
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| المؤلفون: | Sam Beddar, Jerimy C. Polf, S Peterson, Dennis S. Mackin, Rajesh Panthi, Paul Maggi |
| المصدر: | IEEE Transactions on Radiation and Plasma Medical Sciences. 5:383-391 |
| بيانات النشر: | Institute of Electrical and Electronics Engineers (IEEE), 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Physics, Range (particle radiation), Proton, Gamma ray, Electron, Radiation, Atomic and Molecular Physics, and Optics, Pencil (optics), Nuclear physics, Physics::Accelerator Physics, Radiology, Nuclear Medicine and imaging, Neutron, Nuclear Experiment, Instrumentation, Proton therapy |
| الوصف: | The purpose of this study was to determine the types, proportions, and energies of secondary particle interactions in a Compton camera (CC) during the delivery of clinical proton beams. The delivery of clinical proton pencil beams ranging from 70 to 200 MeV incident on a water phantom was simulated using Geant4 software (version 10.4). The simulation included a CC similar to the configuration of a Polaris J3 CC designed to image prompt gammas (PGs) emitted during proton beam irradiation for the purpose of in vivo range verification. The interaction positions and energies of secondary particles in each CC detector module were scored. For a 150-MeV proton beam, a total of 156 688(575) secondary particles per 108 protons, primarily composed of gamma rays (46.31%), neutrons (41.37%), and electrons (8.88%), were found to reach the camera modules, and 79.37% of these particles interacted with the modules. Strategies for using CCs for proton range verification should include methods of reducing the large neutron backgrounds and low-energy non-PG radiation. The proportions of interaction types by module from this study may provide information useful for background suppression. |
| تدمد: | 2469-7303 2469-7311 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5823b9dba617dd978d99699fc4675f67Test https://doi.org/10.1109/trpms.2020.3030166Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....5823b9dba617dd978d99699fc4675f67 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 24697303 24697311 |
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