Association of human leukocyte antigen mismatches between donor‐recipient and donor‐donor in pancreas after kidney transplant recipients
| العنوان: | Association of human leukocyte antigen mismatches between donor‐recipient and donor‐donor in pancreas after kidney transplant recipients |
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| المؤلفون: | Didier A. Mandelbrot, Arjang Djamali, Dixon B. Kaufman, Bridget M. Welch, Sandesh Parajuli, Hans W. Sollinger, Jon S. Odorico |
| المصدر: | Transplant International. 34:2803-2815 |
| بيانات النشر: | Frontiers Media SA, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Graft Rejection, Transplantation, medicine.medical_specialty, Kidney, business.industry, Graft Survival, Pancreas graft, Human leukocyte antigen, Kidney Transplantation, HLA Mismatch, Kidney transplant, Gastroenterology, medicine.anatomical_structure, HLA Antigens, Internal medicine, Cohort, medicine, Humans, Pancreas Transplantation, Pancreas, business |
| الوصف: | The effects of HLA mismatching on pancreas outcomes among pancreas after kidney (PAK) recipients are undefined. Outcomes might potentially differ depending on whether there is a mismatch between pancreas donor and recipient (PD-R) or pancreas donor and kidney donor(PD-KD). All primary PAK at our centre were included in this study. Patients were divided into two groups based on the degree of HLA mismatching: low (L-MM) as 0-4 and high (H-MM) as 5-6. We analysed all (N = 73) PAK for PD-R mismatch and the subset of PAK for PD-KD mismatch (N = 71). Comparing PD-R L-MM (n = 39) and H-MM (n = 34) PAKs, we observed no difference in the rate of pancreas graft failure. There was also no difference in the rate of rejection (L-MM 33% vs. H-MM 41%) or the severity of rejection. However, we observed a significantly (P |
| تدمد: | 1432-2277 0934-0874 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55a4d50eff026cfa96f6959748c6a9d4Test https://doi.org/10.1111/tri.14138Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....55a4d50eff026cfa96f6959748c6a9d4 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14322277 09340874 |
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