Health-related quality of life after open and robot-assisted radical prostatectomy in low- and intermediate-risk prostate cancer patients: a propensity score-matched analysis
| العنوان: | Health-related quality of life after open and robot-assisted radical prostatectomy in low- and intermediate-risk prostate cancer patients: a propensity score-matched analysis |
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| المؤلفون: | Alexander Kretschmer, Michael Chaloupka, Alexander Buchner, Frank Strittmatter, Philipp Weinhold, Robert Bischoff, Thilo Westhofen, Armin J. Becker, Christian G. Stief, Friedrich Jokisch |
| المصدر: | World Journal of Urology |
| بيانات النشر: | Springer Berlin Heidelberg, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | medicine.medical_specialty, Urology, medicine.medical_treatment, Health-related quality of life, 030232 urology & nephrology, Logistic regression, 03 medical and health sciences, Prostate cancer, 0302 clinical medicine, Quality of life, Internal medicine, Clinical endpoint, Robot-assisted radical prostatectomy, Medicine, Urinary continence, business.industry, Prostatectomy, EORTC QLQ-C30, medicine.disease, humanities, 030220 oncology & carcinogenesis, Cohort, Propensity score matching, Original Article, business, Open radical prostatectomy |
| الوصف: | Purpose Introduction of robot-assisted radical prostatectomy (RARP) has revolutionized the therapeutic landscape of organ-confined prostate cancer (PCa). However, comparative analyses focused on health-related quality of life (HRQOL) after RARP and open retropubic prostatectomy (ORP) are sparse. Methods In the current retrospective analysis,inclusion criteria encompassed PSA ≤ 10 ng/ml, ≤ pT2c, ISUP ≤ 3, age ≤ 65 years, and preoperative continence. A propensity score-matched patient cohort [n = 418 (ORP: 209, RARP: 209)] was created and HRQOL was prospectively assessed based on validated questionnaires (EORTC QLQ-C30) preoperatively, 3 months, 12 months, and 24 months postoperatively. Primary endpoint was good general HRQOL based on previously published cut-off values. Erectile function was measured via IIEF-5, urinary continence via ICIQ-SF questionnaire. Multivariable analysis included binary logistic regression models (p |
| اللغة: | English |
| تدمد: | 1433-8726 0724-4983 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5514343baa8c6de7a73a8d02e5407504Test http://europepmc.org/articles/PMC8249262Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....5514343baa8c6de7a73a8d02e5407504 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14338726 07244983 |
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