A multi‐institutional study of salivary gland cytopathology: Application of the Milan System for Reporting Salivary Gland Cytopathology in Japan
| العنوان: | A multi‐institutional study of salivary gland cytopathology: Application of the Milan System for Reporting Salivary Gland Cytopathology in Japan |
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| المؤلفون: | Yukiya Hirata, Makoto Urano, Kayoko Higuchi, Mariko Obayashi, Yuichiro Tada, Toshitaka Nagao, Akihiko Kawahara, Mana Fukushima, Yoko Zukeran, Koki Moriyoshi, Jun Akiba, Masato Nakaguro, Shinnichi Sakamoto, Hidetaka Yamamoto, Miwako Nogami, Kazuya Kuraoka, Taku Kato, Maki Tanigawa, Kana Kira |
| المصدر: | Cancer Cytopathology. 130:30-40 |
| بيانات النشر: | Wiley, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Cancer Research, medicine.medical_specialty, Suspicious for Malignancy, Salivary gland, medicine.diagnostic_test, business.industry, Biopsy, Fine-Needle, Salivary Gland Neoplasms, Malignancy, medicine.disease, Salivary Glands, medicine.anatomical_structure, Fine-needle aspiration, Japan, Oncology, Cytopathology, Cytology, medicine, Atypia, Humans, Salivary gland neoplasm, Radiology, business, Retrospective Studies |
| الوصف: | Background The Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) is a risk-stratification reporting system that was introduced in 2018. The objective of this multi-institutional study was to evaluate the utility of the MSRSGC in Japan. Methods In total, 1608 fine-needle aspiration samples with matching histologic diagnoses were retrieved from 12 large institutions in Japan. The diagnostic categories of the MSRSGC were assigned prospectively or retrospectively, and the results were compared with the histologic diagnoses. Results The cases were classified as follows: nondiagnostic, 18.1%; non-neoplastic, 4.1%; atypia of undetermined significance, 11.5%; neoplasm-benign, 43.7%; salivary gland neoplasm of uncertain malignant potential, 9.6%; suspicious for malignancy, 3.6%; and malignant, 9.4%. The risk of neoplasm and the risk of malignancy in each MSRSGC category were as follows: nondiagnostic, 72.9% and 13.4%, respectively; non-neoplastic, 15.2% and 9.1%, respectively; atypia of undetermined significance, 77.9% and 24.9%, respectively; neoplasm-benign, 99% and 1.8%, respectively; salivary gland neoplasm of uncertain malignant potential, 94.8% and 37%, respectively; suspicious for malignancy, 100% and 89.7%, respectively; and malignant, 100% and 99.3%, respectively. The accuracy of the MSRSGC for diagnosing neoplasms was 97.8%, and its accuracy for diagnosing malignancy was 97.3%. Institutions that used Romanowsky-stained preparations had lower nondiagnostic rates and lower risks of neoplasm and malignancy in the non-neoplastic category. Conclusions The MSRSGC is useful for risk stratification and quality control. Widespread use of the MSRSGC would improve the accuracy of salivary gland cytology and lead to better patient care in Japan. |
| تدمد: | 1934-6638 1934-662X |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5274d5a0c30ec34614c6a37a22a715a6Test https://doi.org/10.1002/cncy.22505Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....5274d5a0c30ec34614c6a37a22a715a6 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19346638 1934662X |
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