Airways Remodelling in Asthma: No Doubt, No More?
العنوان: | Airways Remodelling in Asthma: No Doubt, No More? |
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المؤلفون: | Giovanni Bonsignore, Pascal Chanez, Antonio M. Vignola, François-B. Michel, Jean Bousquet, Alison M. Campbell |
المصدر: | International Archives of Allergy and Immunology. 107:211-214 |
بيانات النشر: | S. Karger AG, 1995. |
سنة النشر: | 1995 |
مصطلحات موضوعية: | Respiratory System, Immunology, Chronic inflammatory disease, Epithelium, Extracellular matrix, Smooth muscle, medicine, Humans, Immunology and Allergy, Airway Remodelling, Growth Substances, Asthma, Inflammation, Mucous Membrane, business.industry, Macrophages, Airway inflammation, Muscle, Smooth, General Medicine, Fibroblasts, respiratory system, medicine.disease, Extracellular Matrix, respiratory tract diseases, Cytokines, business, Myofibroblast |
الوصف: | Asthma is a chronic inflammatory disease of the airways invariably associated with healing. Remodelling of the airways can be demonstrated by the activation of airways macrophages, the release of growth factors and fibrogenic cytokines, the activation of fibroblasts and myofibroblast, elastolysis and elastosynthesis, collagen deposition, increased synthesis and release of extracellular matrix components, and an increased mass of smooth muscle and mucous glands. However, the control of remodelling is still poorly understood. |
تدمد: | 1423-0097 1018-2438 |
الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::511e2440ac13f351760d79725bb327c3Test https://doi.org/10.1159/000236980Test |
حقوق: | CLOSED |
رقم الانضمام: | edsair.doi.dedup.....511e2440ac13f351760d79725bb327c3 |
قاعدة البيانات: | OpenAIRE |
تدمد: | 14230097 10182438 |
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