Effect of Timing of Staged Percutaneous Coronary Intervention on Clinical Outcomes in Patients With Acute Coronary Syndromes
| العنوان: | Effect of Timing of Staged Percutaneous Coronary Intervention on Clinical Outcomes in Patients With Acute Coronary Syndromes |
|---|---|
| المؤلفون: | Yasushi Ueki, Thomas Pilgrim, Christian Zanchin, Fabien Praz, Sarah Bär, Thomas Zanchin, Sylvain Losdat, Jonas Lanz, George C.M. Siontis, Raminta Kavaliauskaite, Lorenz Räber, Jonas Dominik Häner, Stephan Windecker, Tatsuhiko Otsuka, Stefan Stortecky |
| المصدر: | Otsuka, Tatsuhiko; Bär, Sarah; Losdat, Sylvain; Kavaliauskaite, Raminta; Ueki, Yasushi; Zanchin, Christian; Lanz, Jonas; Praz, Fabien; Häner, Jonas; Siontis, George C.M.; Zanchin, Thomas; Stortecky, Stefan; Pilgrim, Thomas; Windecker, Stephan; Räber, Lorenz (2021). Effect of Timing of Staged Percutaneous Coronary Intervention on Clinical Outcomes in Patients With Acute Coronary Syndromes. Journal of the American Heart Association, 10(23), e023129. American Heart Association 10.1161/JAHA.121.023129 <http://dx.doi.org/10.1161/JAHA.121.023129Test> Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 23 (2021) |
| بيانات النشر: | American Heart Association, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Staged Percutaneous Coronary Intervention, medicine.medical_specialty, Acute coronary syndrome, Time Factors, medicine.medical_treatment, multivessel coronary artery disease, 610 Medicine & health, Revascularization, acute coronary syndrome, Cohort Studies, Percutaneous Coronary Intervention, Internal medicine, Medicine, Humans, Diseases of the circulatory (Cardiovascular) system, business.industry, Cardiogenic shock, Hazard ratio, Percutaneous coronary intervention, medicine.disease, Patient Discharge, Cardiac surgery, Treatment Outcome, RC666-701, Conventional PCI, staged percutaneous coronary intervention, Cardiology, Cardiology and Cardiovascular Medicine, business |
| الوصف: | Background Complete revascularization reduces cardiovascular events in patients with acute coronary syndromes (ACSs) and multivessel disease. The optimal time point of non–target‐vessel percutaneous coronary intervention (PCI) remains a matter of debate. The aim of this study was to investigate the impact of early ( Methods and Results All patients with ACS undergoing planned staged PCI from 2009 to 2017 at Bern University Hospital, Switzerland, were analyzed. Patients with cardiogenic shock, in‐hospital staged PCI, staged cardiac surgery, and multiple staged PCIs were excluded. The primary end point was all‐cause death, recurrent myocardial infarction and urgent premature non–target‐vessel PCI. Of 8657 patients with ACS, staged revascularization was planned in 1764 patients, of whom 1432 patients fulfilled the eligibility criteria. At 1 year, there were no significant differences in the crude or adjusted rates of the primary end point (7.8% early versus 10.8% late, hazard ratio [HR], 0.72 [95% CI, 0.47–1.10], P =0.129; adjusted HR, 0.80 [95% CI, 0.50–1.28], P =0.346) and its individual components (all‐cause death: 1.5% versus 2.9%, HR, 0.52 [95% CI, 0.20–1.33], P =0.170; adjusted HR, 0.62 [95% CI, 0.23–1.67], P =0.343; recurrent myocardial infarction: 4.2% versus 4.4%, HR, 0.97 [95% CI, 0.475–1.10], P =0.924; adjusted HR, 1.03 [95% CI, 0.53–2.01], P =0.935; non–target‐vessel PCI, 3.9% versus 5.7%, HR, 0.97 [95% CI, 0.53–1.80], P =0.928; adjusted HR, 1.19 [95% CI, 0.61–2.34], P =0.609). Conclusions In this single‐center cohort study of patients with ACS scheduled to undergo staged PCI after hospital discharge, early ( Registration URL: https://www.clinicaltrials.govTest ; Unique identifier: NCT02241291. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f5faafc95122243e76ce5589e7d926bTest https://boris.unibe.ch/161708/8/Otsuka_JAmHeartAssoc_2021.pdfTest |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....4f5faafc95122243e76ce5589e7d926b |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |