Chegou a Hora de uma Nova Terapia Padrão para a Insuficiência Cardíaca com Fração de Ejeção Reduzida?
| العنوان: | Chegou a Hora de uma Nova Terapia Padrão para a Insuficiência Cardíaca com Fração de Ejeção Reduzida? |
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| المؤلفون: | Eduardo Thadeu de Oliveira Correia, Letícia Mara dos Santos Barbetta, Evandro Tinoco Mesquita |
| المصدر: | Arquivos Brasileiros de Cardiologia, Vol 117, Iss 1, Pp 149-152 (2021) Arquivos Brasileiros de Cardiologia |
| بيانات النشر: | Sociedade Brasileira de Cardiologia (SBC), 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | medicine.medical_specialty, Neprilisina, Angiotensins, Angiotensinas, Insuficiência Cardíaca, Ventricular Dysfunction, Left, Mineralocorticoid receptor, Quality of life, Drug Therapy, Internal medicine, Renin–angiotensin system, medicine, Humans, Diseases of the circulatory (Cardiovascular) system, Carta Científica, Mortality, Heart Failure, Hospitalização, Ejection fraction, business.industry, Ventricular Modeling, Stroke Volume, medicine.disease, Hospitalization, Heart failure, RC666-701, Remodelação Ventricular, Cardiology, Mortalidade, Neprilysin, Cardiology and Cardiovascular Medicine, business, Volume Sistólico, Tratamento Farmacológico, Healthcare system |
| الوصف: | Heart failure (HF) with reduced ejection fraction (HFrEF) leads to mortality and impairment in one’s quality of life, and causes a major impact on the healthcare system. Despite trials showing the benefits of angiotensin receptor–neprilysin inhibitor (ARNI) over angiotensin-converting enzyme inhibitors (ACEi), and the superiority of sodium-glucose cotransporter-2 inhibitors (SGLT2i) over placebos, current guidelines still recommend ACEi, mineralocorticoid receptor antagonists (MRA), and beta-blockers as first-line therapy in HFrEF.1 - 3In this letter, we will discuss the potential benefits and risks of adopting ARNI and SGLT2i as first-line therapies in HFrEF. |
| اللغة: | English |
| تدمد: | 1678-4170 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46567a4924903dfde8db74b3a32e8befTest http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2021000900149&tlng=enTest |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....46567a4924903dfde8db74b3a32e8bef |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 16784170 |
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