Ambient UV, personal sun exposure and risk of multiple primary melanomas
| العنوان: | Ambient UV, personal sun exposure and risk of multiple primary melanomas |
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| المؤلفون: | Bruce K. Armstrong, Amanda J. Hummer, Roberto Zanetti, Beth Theis, Terence Dwyer, Urvi Mujumdar, Hoda Anton Culver, Richard P. Gallagher, Timothy R. Rebbeck, Melisa Litchfield, Marianne Berwick, Robert C. Millikan, Peter A. Kanetsky, Chris Goumas, Colin B. Begg, Klaus J. Busam, Nancy E. Thomas, Lynn From, Loraine D. Marrett, Anne Kricker |
| المصدر: | Cancer Causes & Control. 18:295-304 |
| بيانات النشر: | Springer Science and Business Media LLC, 2007. |
| سنة النشر: | 2007 |
| مصطلحات موضوعية: | Adult, Male, Cancer Research, medicine.medical_specialty, Neoplasms, Radiation-Induced, Skin Neoplasms, Adolescent, Ultraviolet Rays, Radiation induced, Radiation Dosage, Article, Neoplasms, Multiple Primary, European origin, Risk Factors, Occupational Exposure, Odds Ratio, medicine, Humans, Child, skin and connective tissue diseases, Melanoma, neoplasms, Sunlight, integumentary system, business.industry, Environmental Exposure, Environmental exposure, Middle Aged, medicine.disease, Dermatology, Oncology, Multicenter study, Female, Sun exposure, Occupational exposure, business, Risk Reduction Behavior |
| الوصف: | Sun exposure is the main cause of melanoma in populations of European origin. No previous study has examined the effect of sun exposure on risk of multiple primary melanomas compared with people who have one melanoma.We identified and enrolled 2,023 people with a first primary melanoma (controls) and 1,125 with multiple primary melanomas (cases) in seven centers in four countries, recorded their residential history to assign ambient UV and interviewed them about their sun exposure.Risk of multiple primary melanomas increased significantly (P0.05) to OR=2.10 for the highest exposure quarter of ambient UV irradiance at birth and 10 years of age, to OR=1.38 for lifetime recreational sun exposure, to OR=1.85 for beach and waterside activities, to OR=1.57 for vacations in a sunnier climate, to OR=1.50 for sunburns. Occupational sun exposure did not increase risk (OR=1.03 for highest exposure). Recreational exposure at any age increased risk and appeared to add to risk from ambient UV in early life.People who have had a melanoma can expect to reduce their risk of a further melanoma by reducing recreational sun exposure whatever their age. The same is probably true for a person who has never had a melanoma. |
| تدمد: | 1573-7225 0957-5243 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44406fc90604812de7768af873e102dbTest https://doi.org/10.1007/s10552-006-0091-xTest |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....44406fc90604812de7768af873e102db |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15737225 09575243 |
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