Autoimmune comorbidities in Hashimoto’s thyroiditis: different patterns of association in adulthood and childhood/adolescence
| العنوان: | Autoimmune comorbidities in Hashimoto’s thyroiditis: different patterns of association in adulthood and childhood/adolescence |
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| المؤلفون: | Alfredo Campenni, E Cama, F. De Luca, Rosaria Maddalena Ruggeri, Giuseppe Giuffrida, Malgorzata Wasniewska, Angela Alibrandi, Rosaria Certo, Francesco Trimarchi |
| المصدر: | European Journal of Endocrinology. 176:133-141 |
| بيانات النشر: | Oxford University Press (OUP), 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | Adult, Male, 0301 basic medicine, medicine.medical_specialty, Adolescent, Cross-sectional study, Endocrinology, Diabetes and Metabolism, 030209 endocrinology & metabolism, Comorbidity, Hashimoto Disease, Vitiligo, Thyroiditis, Coeliac disease, Autoimmune Diseases, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, Internal medicine, Prevalence, medicine, Humans, Young adult, Child, Aged, Aged, 80 and over, Type 1 diabetes, Hashimoto's Thyroiditis, non-thyroidal autoimmune diseases, business.industry, Hashimoto's Thyroiditis, Autoantibody, General Medicine, Middle Aged, medicine.disease, non-thyroidal autoimmune diseases, Cross-Sectional Studies, 030104 developmental biology, Child, Preschool, Female, business |
| الوصف: | Objective Hashimoto’s thyroiditis (HT), the most common autoimmune thyroid disease at any age, is often associated with other autoimmune diseases. The present study was aimed to describe the type and frequency of non-thyroidal autoimmune diseases (NTADs) in HT patients and to delineate the clinical pattern of diseases clustering in pediatric/adolescent and adult age. Design Cross-sectional study. Methods 1053 newly diagnosed HT patients (500 adults (467 F, mean age 40.2 ± 13.7 years) and 553 children/adolescents (449 F, mean age 11.1 ± 3.0 years)) were evaluated for common NTADs by means of careful recording of medical history, physical examination and assessment of selected autoantibody profiles. Results The prevalence of associated NTADs was significantly higher in adults than that in pediatric/adolescent HT patients (P P P Conclusions Age at HT presentation may influence autoimmune diseases clustering, favoring the association of specific NTADs in different ages of life. Moreover, the association between HT and NTADs increases with age and occurs most frequently in adults. |
| تدمد: | 1479-683X 0804-4643 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41e408a41b63ad876215ab5bb0a8486cTest https://doi.org/10.1530/eje-16-0737Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....41e408a41b63ad876215ab5bb0a8486c |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1479683X 08044643 |
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