Red blood cell distribution width predicts two-hours plasma glucose levels during OGTT
| العنوان: | Red blood cell distribution width predicts two-hours plasma glucose levels during OGTT |
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| المؤلفون: | Cesare Tripolino, Maria Serena De Franceschi, Claudio Carallo, Concetta Irace, Agostino Gnasso, Faustina Scavelli |
| المصدر: | Clinical Hemorheology and Microcirculation. 62:63-69 |
| بيانات النشر: | IOS Press, 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | Blood Glucose, Male, medicine.medical_specialty, Physiology, Blood lipids, 030209 endocrinology & metabolism, Type 2 diabetes, 030204 cardiovascular system & hematology, Carbohydrate metabolism, Gastroenterology, 03 medical and health sciences, 0302 clinical medicine, Physiology (medical), Internal medicine, Diabetes mellitus, Humans, Medicine, Glucose tolerance test, medicine.diagnostic_test, business.industry, Complete blood count, Red blood cell distribution width, Hematology, Glucose Tolerance Test, Middle Aged, medicine.disease, Cross-Sectional Studies, Blood pressure, Endocrinology, Diabetes Mellitus, Type 2, Erythrocyte Count, Female, Cardiology and Cardiovascular Medicine, business |
| الوصف: | OBJECTIVE Red blood cell distribution width (RDW) is a numerical measure, reported as part of a standard complete blood count, usually employed for differential diagnosis of anemic state. Some lines of evidence demonstrate that RDW associates with type 2 diabetes incidence and its complications. To further explore the role of RDW as predictor of abnormal glucose metabolism, we have analyzed the relationship between RDW and 2-hours plasma glucose concentration during an oral glucose tolerance test (OGTT). METHODS Forty-five outpatients were enrolled for the present study. Participants underwent 75 g OGTT and measurements of hematological parameters. Cardiovascular disease risk factors (blood pressure, blood lipids, cigarette smoking, obesity) were evaluated by routine methods. RESULTS In simple regression analysis 2-hours post-load glucose was directly associated with age (r = 0.36, p = 0.01), fasting glucose levels (r = 0.40, p = 0.002) and RDW (r = 0.31, p = 0.037). In multiple regression analysis fasting glucose, RDW, triglycerides and age significantly and independently predicted 2-hours plasma glucose (p < 0.01 for all coefficients). CONCLUSION The present findings demonstrate that RDW associates with plasma glucose concentration after a 75-g oral glucose tolerance test. Our results highlight the role of RDW as predictor of glucose metabolism disturbance. |
| تدمد: | 1875-8622 1386-0291 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::408bfe6fad3ccaab86669ef7c045f883Test https://doi.org/10.3233/ch-151947Test |
| رقم الانضمام: | edsair.doi.dedup.....408bfe6fad3ccaab86669ef7c045f883 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 18758622 13860291 |
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