Neuropsychological assessments and cognitive profile mostly associated with shunt surgery in idiopathic normal pressure hydrocephalus patients: diagnostic and predictive parameters and practical implications
| العنوان: | Neuropsychological assessments and cognitive profile mostly associated with shunt surgery in idiopathic normal pressure hydrocephalus patients: diagnostic and predictive parameters and practical implications |
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| المؤلفون: | Yosef Laviv, Mor Nimni, Penina Weiss, Chen Cohen |
| المصدر: | Acta Neurochirurgica. 163:3373-3386 |
| بيانات النشر: | Springer Science and Business Media LLC, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Pediatrics, medicine.medical_specialty, business.industry, Neuropsychology, Cognition, Cognistat, Gold standard (test), Neuropsychological Tests, Executive functions, medicine.disease, Cerebrospinal Fluid Shunts, Hydrocephalus, Normal Pressure, Cognitive test, Normal pressure hydrocephalus, Humans, Medicine, Surgery, Neurology (clinical), Cognitive decline, business, Retrospective Studies |
| الوصف: | Cognitive decline is a well-documented feature of idiopathic normal pressure hydrocephalus (iNPH) that can be reversible following cerebrospinal fluid tap tests (CSF-TT). The current gold standard for selecting iNPH patients for shunt surgery is measurable improvement in gait tests following CSF–TT. However, the diagnostic significance and predictive role of pre-surgical cognitive evaluations in probable iNPH patients is still controversial. To find the neuropsychological (NPSY) tests and cognitive aspects mostly associated with shunt surgery in iNPH. A retrospective comparison between probable iNPH patients who, after undergoing CSF–TT with gait and cognitive evaluations, ended up receiving a shunt (group 1) and probable iNPH patients who ended up with no shunt surgery (group 2). Differences in the diagnostic and predictive results of variety of NPSY tests at baseline, pre-CSF-TT, and post-CSF-TT were used for thorough statistical calculations. A total of 147 patients with probable iNPH were included. Of those, 58 (39.45%, group 1) patients underwent shunt surgery, while 89 (60.55%, group 2) did not. For the vast majority of the cognitive tests used, no statistically significant differences were found between the groups at baseline (pre-CSF-TT). Following CSF-TT, the “naming” component of the Cognistat test was the only single test to show statically significant difference in improvement between the two groups. Combining at least two tests led to increased levels of accuracy and specificity; however, the sensitivity remained |
| تدمد: | 0942-0940 0001-6268 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e8c00e63f8bcb8be37cdcd5aabcc650Test https://doi.org/10.1007/s00701-021-04976-zTest |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....3e8c00e63f8bcb8be37cdcd5aabcc650 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 09420940 00016268 |
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