Niveles de colesterol no HDL en la población chilena y su asociación con enfermedad cardiovascular y diabetes mellitus: estudio de corte transversal en Encuesta Nacional de Salud 2009-2010
| العنوان: | Niveles de colesterol no HDL en la población chilena y su asociación con enfermedad cardiovascular y diabetes mellitus: estudio de corte transversal en Encuesta Nacional de Salud 2009-2010 |
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| المؤلفون: | Luis Villarroel, Attilio Rigotti, Aranzazu Jugo, Guadalupe Echeverría, María Consuelo Alé, Alberto Maiz |
| المصدر: | Revista médica de Chile v.147 n.11 2019 SciELO Chile CONICYT Chile instacron:CONICYT |
| بيانات النشر: | SciELO Agencia Nacional de Investigacion y Desarrollo (ANID), 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | medicine.medical_specialty, education.field_of_study, business.industry, Cross-sectional study, Cholesterol, Population, Blood lipids, General Medicine, Disease, Diabetes Mellitus Type 2, medicine.disease, chemistry.chemical_compound, chemistry, Cardiovascular Diseases, Internal medicine, Diabetes mellitus, Medicine, lipids (amino acids, peptides, and proteins), Young adult, business, education, VLDL, Cohort study |
| الوصف: | Background Despite aggressive treatment aimed at lowering LDL cholesterol (LDL-C) levels with statins, there is a high residual prevalence of cardiovascular diseases, which may depend on plasma cholesterol transported in other atherogenic lipoproteins. Aims To describe non-HDL cholesterol (non-HDL-C) levels in the Chilean population and their association with diabetes mellitus and cardiovascular disease. To evaluate compliance with non-HDL-C therapeutic goals -according to individual cardiovascular risk- at different levels of triglycerides, in comparison with LDL-C goal achievement. Material and Methods: We analyzed data from 2,792 Chilean subjects aged ≥ 15 years who were included in the 2009-2010 National Health Survey and had valid data for blood lipids, diabetes, and cardiovascular disease. Results Forty five percent of subjects had high non-HDL-C levels. The proportion of diabetic and non-diabetic subjects with high non-HDL-C levels was 81 and 42%, respectively (p < 0.01). A significant discordance was observed in the achievement of therapeutic objectives when LDL-C or non-HDL-C levels were considered, particularly in presence of triglycerides ≥ 150 mg/dl. Namely, 8% of the population showed elevated levels of high non-HDL-C despite adequate LDL-C levels. Conclusions Evaluation and management of elevated non-HDL-C in patients with adequate levels of LDL-C seems worthwhile considering the discordance observed between these blood cholesterol fractions. This strategy may be effective to reduce the residual cardiovascular risk in the Chilean population. |
| وصف الملف: | text/html |
| تدمد: | 0034-9887 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e22a11ed60e76b38a3f63e23d9331ccTest https://doi.org/10.4067/s0034-98872019001101365Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....3e22a11ed60e76b38a3f63e23d9331cc |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 00349887 |
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