Hepatic steroid inactivating enzymes, hepatic portal blood flow and corpus luteum blood perfusion in cattle
| العنوان: | Hepatic steroid inactivating enzymes, hepatic portal blood flow and corpus luteum blood perfusion in cattle |
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| المؤلفون: | C. G. Hart, B. E. Voelz, Caleb O Lemley, KE Brockus |
| المصدر: | Reproduction in Domestic Animals. 53:751-758 |
| بيانات النشر: | Wiley, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | 0301 basic medicine, medicine.medical_specialty, CYP3A, Luteal phase, 03 medical and health sciences, Endocrinology, Corpus Luteum, Pregnancy, Internal medicine, Lactation, medicine, Animals, Progesterone, reproductive and urinary physiology, biology, Portal Vein, business.industry, 0402 animal and dairy science, food and beverages, Cytochrome P450, Ultrasonography, Doppler, 04 agricultural and veterinary sciences, Blood flow, medicine.disease, 040201 dairy & animal science, 030104 developmental biology, medicine.anatomical_structure, Liver, biology.protein, Cattle, Female, Animal Science and Zoology, business, Corpus luteum, Perfusion, Liver Circulation, Biotechnology |
| الوصف: | Production from the corpus luteum (CL) and/or hepatic steroid inactivation impacts peripheral concentrations of P4, which can alter reproductive performance. Our primary objective was to examine hepatic steroid inactivating enzymes, portal blood flow, and luteal blood perfusion at 10 days post-insemination in pregnant versus non-pregnant beef and dairy cows. Twenty early lactation Holstein cows and 20 lactating commercial beef cows were utilized for this study. At day 10 post-insemination, hepatic portal blood flow and CL blood perfusion were measured via Doppler ultrasonography. Liver biopsies were collected and frozen for later determination of cytochrome P450 1A (CYP1A), 2C (CYP2C), 3A (CYP3A), uridine diphosphate-glucuronosyltransferase (UGT) and aldo-keto reductase 1C (AKR1C) activities. Pregnancy was determined at day 30 post-insemination and treatment groups were retrospectively assigned as pregnant or non-pregnant. Data were analyzed using the mixed procedure of SAS. Steroid metabolizing enzyme activity was not different (p > .10) between pregnant versus non-pregnant beef or dairy cows. Hepatic portal blood flow tended (p |
| تدمد: | 1439-0531 0936-6768 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c8259893271a3a7fe3601cb69e1ab26Test https://doi.org/10.1111/rda.13166Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....3c8259893271a3a7fe3601cb69e1ab26 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14390531 09366768 |
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