Therapeutic potential of ADAM17 modulation in gastric cancer through regulation of the EGFR and TNF-α signalling pathways

التفاصيل البيبلوغرافية
العنوان: Therapeutic potential of ADAM17 modulation in gastric cancer through regulation of the EGFR and TNF-α signalling pathways
المؤلفون: Danhao Tao, Jinbing Sun, Kuangyi Lu, Jianlong Jiang, Qiao Chen, Zhong Chen
المصدر: Molecular and cellular biochemistry. 426(1-2)
سنة النشر: 2016
مصطلحات موضوعية: 0301 basic medicine, Male, Pathology, medicine.medical_specialty, Clinical Biochemistry, Biology, ADAM17 Protein, Gene Expression Regulation, Enzymologic, Metastasis, Flow cytometry, 03 medical and health sciences, 0302 clinical medicine, Stomach Neoplasms, Cell Line, Tumor, medicine, Humans, Neoplasm Invasiveness, Neoplasm Metastasis, RNA, Small Interfering, Molecular Biology, Cell Proliferation, Gene knockdown, medicine.diagnostic_test, Cell growth, Tumor Necrosis Factor-alpha, Cancer, Cell Biology, General Medicine, medicine.disease, Neoplasm Proteins, ErbB Receptors, Gene Expression Regulation, Neoplastic, 030104 developmental biology, Apoptosis, 030220 oncology & carcinogenesis, Gene Knockdown Techniques, Cancer research, Immunohistochemistry, Tumor necrosis factor alpha, Signal Transduction
الوصف: A disintegrin and metalloproteinase 17 (ADAM17) is highly expressed in various tumours and affects tumour progression. In this study, ADAM17 expression in 60 gastric cancer and 20 normal gastric mucosal tissues was assessed using immunohistochemistry. ADAM17 expression was higher in gastric cancer tissues than in normal gastric mucosal tissues (P
تدمد: 1573-4919
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3be21a606bec07758be9059a70b3eb16Test
https://pubmed.ncbi.nlm.nih.gov/27878499Test
حقوق: CLOSED
رقم الانضمام: edsair.doi.dedup.....3be21a606bec07758be9059a70b3eb16
قاعدة البيانات: OpenAIRE