Nuclear morphometry and ploidy of normal and neoplastic haemocytes in mussels
| العنوان: | Nuclear morphometry and ploidy of normal and neoplastic haemocytes in mussels |
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| المؤلفون: | Gabriel Landini, Gionata De Vico, Francesca Carella |
| المساهمون: | Carella, Francesca, DE VICO, Gionata, Landini, Gabriel |
| المصدر: | PLoS ONE, Vol 12, Iss 3, p e0173219 (2017) PLoS ONE |
| بيانات النشر: | Public Library of Science (PLoS), 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | 0301 basic medicine, Pathology, B Cells, Hemocytes, lcsh:Medicine, Severity of Illness Index, White Blood Cells, Spectrum Analysis Techniques, Ploidy, Animal Cells, Neoplasms, Medicine and Health Sciences, Mussels, lcsh:Science, Staining, education.field_of_study, Multidisciplinary, biology, Mytilus, medicine.anatomical_structure, Spectrophotometry, Cellular Types, Anatomy, Algorithms, Research Article, Bivalves, medicine.medical_specialty, Histology, Imaging Techniques, Immune Cells, Immunology, Population, Research and Analysis Methods, 03 medical and health sciences, Multinucleate, Genetics, medicine, Animals, Antibody-Producing Cells, education, Cell Nucleus, Evolutionary Biology, Blood Cells, Ploidies, Population Biology, Morphometry, lcsh:R, Organisms, Biology and Life Sciences, Cell Biology, Molluscs, Mussel, biology.organism_classification, Bivalvia, Invertebrates, Cell nucleus, 030104 developmental biology, Specimen Preparation and Treatment, lcsh:Q, Densitometry, Population Genetics, Feulgen Staining |
| الوصف: | Haemic neoplasia (HN) in bivalves has been reported in association with mass mortality events in various species of molluscs. The aim of this work was to quantify the nuclear morphometry and DNA content of neoplastic cells of mussels Mytilus galloprovincialis affected by HN using nuclear densitometry in Feulgen-stained preparations. The results were also compared with a population of normal mussel haemocytes. We captured 256 images of 3 different neoplasia stages and 120 images of normal haemocytes; thus, a total of 120,166 nuclei were analysed. We extracted 21 morphological parameters from normal and neoplastic nuclei. Eighteen of these parameters were different (P |
| تدمد: | 1932-6203 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b2d6b582e19d8bab018572e12281302Test https://doi.org/10.1371/journal.pone.0173219Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....3b2d6b582e19d8bab018572e12281302 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19326203 |
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