Impact of Bariatric Surgery on Metabolic and Gut Microbiota Profile: a Systematic Review and Meta-analysis
| العنوان: | Impact of Bariatric Surgery on Metabolic and Gut Microbiota Profile: a Systematic Review and Meta-analysis |
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| المؤلفون: | Christina Chatedaki, Vasiliki S. Tasiopoulou, Dimitrios E Magouliotis, Dimitrios Zacharoulis, Eleni Sioka |
| المصدر: | Obesity Surgery. 27:1345-1357 |
| بيانات النشر: | Springer Science and Business Media LLC, 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | Adult, Blood Glucose, Male, 0301 basic medicine, medicine.medical_specialty, Food intake, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Bariatric Surgery, 030209 endocrinology & metabolism, Gut flora, Cochrane Library, law.invention, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Randomized controlled trial, Glucagon-Like Peptide 1, law, Diabetes mellitus, medicine, Humans, Insulin, Obesity, Nutrition and Dietetics, biology, business.industry, digestive, oral, and skin physiology, Middle Aged, biology.organism_classification, medicine.disease, Gastrointestinal Microbiome, Surgery, 030104 developmental biology, Meta-analysis, Peptide YY, Female, business, Amino Acids, Branched-Chain |
| الوصف: | We aim to review the available literature on obese patients treated with bariatric procedures, in order to assess their effect on the metabolic and gut microbiota profiles. A systematic literature search was performed in PubMed, Cochrane library, and Scopus databases, in accordance with the PRISMA guidelines. Twenty-two studies (562 patients) met the inclusion criteria. This study points to significant amelioration of postoperative levels of glucose, insulin, triglycerides, total cholesterol, LDL, HDL, HOMA-IR, food intake, and diabetes remission. Branched-chain amino acids (BCAAs) decreased, while trimethylamine-n-oxide (TMAO); glucagon-like peptide 1, 2 (GLP-1, GLP-2); and peptide YY (PYY) increased postoperatively. Postoperative gut microbiota was similar to that of lean and less obese objects. Well-designed randomized trials are necessary to further assess the host metabolic-microbial cross-talk after bariatric procedures. |
| تدمد: | 1708-0428 0960-8923 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38a0244a18df00e2066e484625c5eb36Test https://doi.org/10.1007/s11695-017-2595-8Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....38a0244a18df00e2066e484625c5eb36 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 17080428 09608923 |
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