Second primary malignancies in postpolycythemia vera and postessential thrombocythemia myelofibrosis: A study on 2233 patients
| العنوان: | Second primary malignancies in postpolycythemia vera and postessential thrombocythemia myelofibrosis: A study on 2233 patients |
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| المؤلفون: | Mora, Barbara, Rumi, Elisa, Guglielmelli, Paola, Barraco, Daniela, Maffioli, Margherita, Rambaldi, Alessandro, Caramella, Marianna, Komrokji, Rami, Gotlib, Jason, Kiladjian, Jean Jacques, Cervantes, Francisco, Devos, Timothy, Palandri, Francesca, De Stefano, Valerio, Ruggeri, Marco, Silver, Richard T., Benevolo, Giulia, Albano, Francesco, Cavalloni, Chiara, Pietra, Barbui, Tiziano, Rotunno, Giada, Cazzola, Mario, Vannucchi, Alessandro Maria, Giorgino, Toni, Passamonti |
| المصدر: | Cancer Medicine Cancer Medicine 8 (2019): 4089–4092. doi:10.1002/cam4.2107 info:cnr-pdr/source/autori:Mora, Barbara and Rumi, Elisa and Guglielmelli, Paola and Barraco, Daniela and Maffioli, Margherita and Rambaldi, Alessandro and Caramella, Marianna and Komrokji, Rami and Gotlib, Jason and Kiladjian, Jean Jacques and Cervantes, Francisco and Devos, Timothy and Palandri, Francesca and De Stefano, Valerio and Ruggeri, Marco and Silver, Richard T. and Benevolo, Giulia and Albano, Francesco and Cavalloni, Chiara and Pietra, Daniela and Barbui, Tiziano and Rotunno, Giada and Cazzola, Mario and Vannucchi, Alessandro Maria and Giorgino, Toni and Passamonti, Francesco/titolo:Second primary malignancies in postpolycythemia vera and postessential thrombocythemia myelofibrosis: A study on 2233 patients/doi:10.1002%2Fcam4.2107/rivista:Cancer Medicine/anno:2019/pagina_da:4089/pagina_a:4092/intervallo_pagine:4089–4092/volume:8 Cancer Medicine, Vol 8, Iss 9, Pp 4089-4092 (2019) |
| بيانات النشر: | Wiley, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Male, 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, Skin Neoplasms, Population, POLYCYTHEMIA-VERA, lcsh:RC254-282, Cohort Studies, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Secondary Myelofibrosis, medicine, Humans, Janus Kinase Inhibitors, Radiology, Nuclear Medicine and imaging, education, Myelofibrosis, Polycythemia Vera, Original Research, education.field_of_study, Science & Technology, JAK inhibitors, business.industry, Incidence, Incidence (epidemiology), fungi, Second malignancy, Secondary myelofibrosis, Clinical Cancer Research, second malignancy, Neoplasms, Second Primary, Second primary cancer, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, medicine.disease, Settore MED/15 - MALATTIE DEL SANGUE, Treatment Outcome, 030104 developmental biology, Primary Myelofibrosis, 030220 oncology & carcinogenesis, Cohort, Second Malignancy, Female, secondary myelofibrosis, business, Life Sciences & Biomedicine, Thrombocythemia, Essential |
| الوصف: | Patients with myeloproliferative neoplasms (MPN) are known to have higher incidence of nonhematological second primary malignancies (SPM) compared to general population. In the MYSEC study on 781 secondary myelofibrosis (SMF) patients, the incidence of SPM after SMF diagnosis resulted 0.98/100 patient-years. When including non-melanoma skin cancers (NMSC), the incidence arose to 1.56/100 patient-years. In SMF, JAK inhibitor treatment was associated only with NMSC occurrence. Then, we merged the MYSEC cohort with a large dataset of PV and ET not evolving into SMF. In this subanalysis, we did not find any correlation between SPM and SMF occurrence. These findings highlight the need of studies aimed at identifying MPN patients at higher risk of SPM. ispartof: CANCER MEDICINE vol:8 issue:9 pages:4089-4092 ispartof: location:United States status: published |
| وصف الملف: | Print-Electronic |
| تدمد: | 2045-7634 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36f82865b053d9a4de4d694e98095e78Test https://doi.org/10.1002/cam4.2107Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....36f82865b053d9a4de4d694e98095e78 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20457634 |
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