Endoscopic and Clinical Factors Affecting the Prognosis of Colorectal Endoscopic Submucosal Dissection-Related Perforation
| العنوان: | Endoscopic and Clinical Factors Affecting the Prognosis of Colorectal Endoscopic Submucosal Dissection-Related Perforation |
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| المؤلفون: | Sang Hyoung Park, Ho-Su Lee, Jeong Sik Byeon, Dong-Hoon Yang, Soon Man Yoon, Jin-Ho Kim, Hyo Jeong Lee, Dong Uk Kang, Seung-Jae Myung, Y.J. Choi, Byong Duk Ye, Suk-Kyun Yang, Kyung-Jo Kim |
| المصدر: | Gut and Liver |
| بيانات النشر: | The Editorial Office of Gut and Liver, 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | Male, Abdominal pain, medicine.medical_specialty, Endoscopic Mucosal Resection, Colon, medicine.medical_treatment, Perforation (oil well), Colonoscopy, Endoscopic mucosal resection, Colonic Diseases, 03 medical and health sciences, 0302 clinical medicine, Intestinal mucosa, Humans, Medicine, Intestinal Mucosa, Intraoperative Complications, Outcome, Retrospective Studies, Perforation, Hepatology, medicine.diagnostic_test, business.industry, Medical record, Gastroenterology, Retrospective cohort study, Clipping (medicine), Middle Aged, Endoscopic submucosal dissection, Prognosis, Surgery, C-Reactive Protein, Intestinal Perforation, 030220 oncology & carcinogenesis, Original Article, Female, 030211 gastroenterology & hepatology, medicine.symptom, Colorectal Neoplasms, business |
| الوصف: | Background/Aims: Although colorectal endoscopic submucosal dissection (ESD)-related perforation is not uncommon, the factors affecting clinical outcomes after perforation have not been investigated. This study was designed to investigate the factors influencing the clinical course of ESD-related colon perforation. Methods: Forty-three patients with colorectal ESD-related perforation were evaluated. The perforations were classified as endoscopic or radiologic perforations. The patients’ medical records and endoscopic pictures were analyzed. Results: The clinical outcomes were assessed by the duration of nil per os, intravenous antibiotics administration, and hospital stays, which were 2.7±1.5, 4.9±2.3, and 5.1±2.3 days, respectively. Multivariate analyses revealed that a larger tumor size, ESD failure, specific endoscopists, and abdominal pain were independently related to a poorer outcome. The time between perforation and clipping was 15.8±25.4 minutes in the endoscopic perforation group. The multivariate analysis of this group indicated that delayed clipping, specific endoscopists, and abdominal pain were independently associated with poorer outcomes. Conclusions: Tumor size, ESD failure, abdominal pain, and the endoscopist were factors that affected the clinical outcomes of patients with colorectal ESD-related perforation. The time between the perforation and clipping was an additional factor influencing the clinical course of endoscopic perforation. Decreasing this time period may improve outcomes. (Gut Liver 2016;10:420-428) |
| تدمد: | 2005-1212 1976-2283 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3537b5b5eb868e35bac485f295d684c8Test https://doi.org/10.5009/gnl15252Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....3537b5b5eb868e35bac485f295d684c8 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20051212 19762283 |
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