Quality of Life before Hyperhidrosis Treatment as a Predictive Factor for Oxybutynin Treatment Outcomes in Palmar and Axillary Hyperhidrosis
| العنوان: | Quality of Life before Hyperhidrosis Treatment as a Predictive Factor for Oxybutynin Treatment Outcomes in Palmar and Axillary Hyperhidrosis |
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| المؤلفون: | Marcelo Passos Teivelis, Taiz Pereira Dozono de Almeida Campbell, Paulo Kauffman, Pedro Puech-Leão, José Ribas Milanez de Campos, Mariana Krutman, Nelson Wolosker |
| المصدر: | Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual) Universidade de São Paulo (USP) instacron:USP |
| بيانات النشر: | Elsevier BV, 2014. |
| سنة النشر: | 2014 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, Adolescent, Treatment outcome, Sweating, Muscarinic Antagonists, Thoracoscopic sympathectomy, Axillary hyperhidrosis, Young Adult, Quality of life, Surveys and Questionnaires, Humans, Hyperhidrosis, Medicine, Child, Oxybutynin, Adverse effect, Retrospective Studies, TORACOSCOPIA, business.industry, General Medicine, Middle Aged, humanities, Predictive factor, Treatment Outcome, Child, Preschool, Quality of Life, Physical therapy, Mandelic Acids, Female, Surgery, medicine.symptom, Cardiology and Cardiovascular Medicine, business, medicine.drug |
| الوصف: | Background Studies have suggested that quality of life (QOL) evaluation before video-assisted thoracoscopic sympathectomy for patients with hyperhidrosis may serve as a predictive factor for positive postoperative outcomes. Our study aims to analyze if this tendency is also observed in patients treated with oxybutynin for palmar and axillary hyperhidrosis. Methods Five hundred sixty-five patients who submitted to a protocol treatment with oxybutynin were retrospectively analyzed between January 2007 and January 2012 and were divided into 2 groups according to QOL assessment before treatment. The groups consisted of 176 patients with “poor” and 389 patients with “very poor” QOL evaluation before oxybutynin treatment. Outcomes involving improvements in QOL and clinical progression of hyperhidrosis were evaluated using a validated clinical questionnaire that was specifically designed to assess satisfaction in patients with excessive sweating. Results Improvements in hyperhidrosis after oxybutynin were observed in 65.5% of patients with very poor pretreatment QOL scores and in 75% of patients with poor pretreatment QOL scores, and the only adverse event associated with oxybutynin treatment was dry mouth, which was observed with greater intensity in patients with very poor initial QOL evaluation. Conclusion Improvements in hyperhidrosis after oxybutynin treatment were similar in both groups, suggesting that QOL before treatment is not a predictive factor for clinical outcomes, contrasting with surgical results that disclose significantly better results in patients with initially poorer QOL analysis. |
| تدمد: | 0890-5096 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30207bb6607d064113de8091f0f819a7Test https://doi.org/10.1016/j.avsg.2013.07.032Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....30207bb6607d064113de8091f0f819a7 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 08905096 |
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