Impact of Incretin-Based Therapies on Adipokines and Adiponectin
| العنوان: | Impact of Incretin-Based Therapies on Adipokines and Adiponectin |
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| المؤلفون: | Habib Yaribeygi, Mina Maleki, Stephen L. Atkin, Amirhossein Sahebkar, Tannaz Jamialahmadi |
| المصدر: | Journal of Diabetes Research Journal of Diabetes Research, Vol 2021 (2021) |
| بيانات النشر: | Hindawi Limited, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Blood Glucose, Endocrinology, Diabetes and Metabolism, Adipokine, Incretin, Review Article, Bioinformatics, Incretins, Diseases of the endocrine glands. Clinical endocrinology, Glucagon-Like Peptide-1 Receptor, Endocrinology, Adipokines, Diabetes mellitus, Diabetes Mellitus, Animals, Humans, Hypoglycemic Agents, Medicine, Secretion, Carbohydrate homeostasis, Adiponectin, business.industry, RC648-665, medicine.disease, Treatment Outcome, business, Biomarkers, Hormone |
| الوصف: | Adipokines are a family of hormones and cytokines with both pro- and anti-inflammatory effects released into the circulation to exert their hormonal effects. Adipokines are closely involved in most metabolic pathways and play an important modulatory role in lipid and carbohydrate homeostasis as they are involved in the pathophysiology of most metabolic disorders. Incretin-based therapy is a newly introduced class of antidiabetic drugs that restores euglycemia through several cellular processes; however, its effect on adipokines expression/secretion is not fully understood. In this review, we propose that incretin-based therapy may function through adipokine modulation that may result in pharmacologic properties beyond their direct antidiabetic effects, resulting in better management of diabetes and diabetes-related complications. |
| تدمد: | 2314-6753 2314-6745 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f401ff9aca5dc970ff33903ca901a61Test https://doi.org/10.1155/2021/3331865Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....2f401ff9aca5dc970ff33903ca901a61 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 23146753 23146745 |
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