Bruusgaard-Mouritsen, M A, Garvey, L H & Johansen, J D 2021, ' Facial contact dermatitis caused by cosmetic-relevant allergens ', Contact Dermatitis, vol. 85, no. 6, pp. 650-659 . https://doi.org/10.1111/cod.13966Test
Background Facial allergic contact dermatitis caused by cosmetic products is common. New allergens in cosmetics continuously emerge. Objectives To investigate characteristics of patients with facial dermatitis between 2010–2019 including patch test results from cosmetic-related allergens and a new test series with cosmetic-relevant natural ingredients (CRNIs). Methods A retrospective study analyzing demographics, clinical characteristics according to MOAHLFA, and patch test results to 27 cosmetic-relevant allergens in facial dermatitis patients. A prospective study evaluating a screening test series with CRNIs in consecutive facial dermatitis patients for one year. These patients received a questionnaire for collecting extra characteristics e.g. concerning quality of life. Results Of 8740 tested patients, 2292 (26.2 had facial dermatitis. Of these, 30.6induced facial dermatitis. The most common cosmetic-related allergens were fragrances and preservatives. The most common patch test positive CRNIs were hydroperoxides of limonene and linalool, and propolis. Potato and peanut were rare, but the most common prick test positive CRNIs, however without any relation to the use of cosmetic products. Facial dermatitis affected nearly all patients′ quality of life and caused limitations to their daily life. Conclusion Updated management and quick diagnosis of facial dermatitis is important to avoid negative impact on patients′ quality of life. This article is protected by copyright. All rights reserved. BackgroundFacial allergic contact dermatitis caused by cosmetic products is common. New allergens in cosmetics continuously emerge.ObjectivesTo investigate characteristics of patients with facial dermatitis (FD) between 2010 and 2019 including patch test results from cosmetic-related allergens and a new test series with cosmetic-relevant natural ingredients (CRNIs).MethodsThis is a retrospective study analysing demographics, clinical characteristics according to MOAHLFA index (male; occupation; atopic dermatitis; hand; leg; face; age ≥ 40 years), and patch test results to 27 cosmetic-relevant allergens in FD patients. A prospective study evaluating a screening test series with CRNIs in consecutive FD patients for 1 year was also conducted. These patients received a questionnaire for collecting extra characteristics (eg, concerning quality of life).ResultsOf 8740 tested patients, 2292 (26.2%) had FD. Of these, 30.6% had cosmetic-induced FD. The most common cosmetic-related allergens were fragrances and preservatives. The most common patch test-positive CRNIs were hydroperoxides of limonene and linalool, and propolis. Potato and peanut were rare, but the most common prick test-positive CRNIs, however, without any relation to the use of cosmetic products. FD affected nearly all patients' quality of life and caused limitations to their daily life.ConclusionsUpdated management and quick diagnosis of FD is important to avoid negative impact on patients' quality of life.
