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Supplementary Figures S1-S5 from Suppression of Deacetylase SIRT1 Mediates Tumor-Suppressive NOTCH Response and Offers a Novel Treatment Option in Metastatic Ewing Sarcoma

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العنوان:	Supplementary Figures S1-S5 from Suppression of Deacetylase SIRT1 Mediates Tumor-Suppressive NOTCH Response and Offers a Novel Treatment Option in Metastatic Ewing Sarcoma
المؤلفون:	Heinrich Kovar, Antonio Llombart-Bosch, Ewa Snaar-Jagalska, Elizabeth R. Lawlor, Katia Scotlandi, Sandra J. Strauss, Verena Berg, Adrienne M. Flanagan, Piero Picci, Raphaela Schwentner, Oscar M. Tirado, Carlos Rodriguez-Galindo, Isidro Machado, Stephan Niedan, Max Kauer, Wietske van der Ent, Argyro Fourtouna, Dave N.T. Aryee, Jozef Ban
بيانات النشر:	American Association for Cancer Research (AACR), 2023.
سنة النشر:	2023
الوصف:	Supplementary Figures S1-S5. MDM4 modulation by HEY1 occurs downstream of TP53 (S1); Modulation of SIRT1 and TP53 induction upon ectopic expression of Flag-tagged HEY1 in the B-cell malignancy cell lines "697" and NALM6, and in primary keratinocytes (S2); The degree of SIRT1 modulation depends on HEY1 levels (S3); Flow-diagram of samples analysed on tissue micro arrays (TMA1, TMA2, TMA3), and FFPE sections used in this study (S4); Kaplan-Meier survival estimates for patients analysed for SIRT1 expression on TMA3 (S5).
الوصول الحر:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29206ec484b8ddfc478456ffc0e0b3f4Test https://doi.org/10.1158/0008-5472.22404542.v1Test
حقوق:	OPEN
رقم الانضمام:	edsair.doi.dedup.....29206ec484b8ddfc478456ffc0e0b3f4
قاعدة البيانات:	OpenAIRE

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