Sex, age, type of diabetes and incidence of atrial fibrillation in patients with diabetes mellitus: a nationwide analysis
| العنوان: | Sex, age, type of diabetes and incidence of atrial fibrillation in patients with diabetes mellitus: a nationwide analysis |
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| المؤلفون: | Alexandre Bodin, Julien Herbert, Gregory Y.H. Lip, Laurent Fauchier, Pierre Henri Ducluzeau, Grégoire Fauchier, Denis Angoulvant, Arnaud Bisson |
| المساهمون: | CHU Trousseau [Tours], Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), Centre Hospitalier Régional Universitaire de Tours (CHRU TOURS), EA4245 - Transplantation, Immunologie, Inflammation [Tours] (T2i), Université de Tours, Physiologie de la reproduction et des comportements [Nouzilly] (PRC), Institut Français du Cheval et de l'Equitation [Saumur]-Université de Tours-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Hôpital Bretonneau, University of Liverpool, Aalborg University [Denmark] (AAU), Université de Tours (UT), Institut Français du Cheval et de l'Equitation [Saumur]-Université de Tours (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE) |
| المصدر: | Cardiovascular Diabetology Cardiovascular Diabetology, BioMed Central, 2021, 20 (1), pp.1-11. ⟨10.1186/s12933-021-01216-7⟩ Bisson, A, Bodin, A, Fauchier, G, Herbert, J, Angoulvant, D, Ducluzeau, P H, Lip, G Y H & Fauchier, L 2021, ' Sex, age, type of diabetes and incidence of atrial fibrillation in patients with diabetes mellitus : a nationwide analysis ', Cardiovascular Diabetology, vol. 20, no. 1, 24 . https://doi.org/10.1186/s12933-021-01216-7Test Cardiovascular Diabetology, Vol 20, Iss 1, Pp 1-11 (2021) |
| بيانات النشر: | Springer Science and Business Media LLC, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Adult, Male, lcsh:Diseases of the circulatory (Cardiovascular) system, medicine.medical_specialty, Databases, Factual, Sex-difference, [SDV]Life Sciences [q-bio], Endocrinology, Diabetes and Metabolism, 030209 endocrinology & metabolism, Type 2 diabetes, 030204 cardiovascular system & hematology, Risk Assessment, 03 medical and health sciences, Sex Factors, 0302 clinical medicine, Risk Factors, Internal medicine, Diabetes mellitus, Prevalence, medicine, Humans, atrial fibrillation, Longitudinal Studies, Aged, Retrospective Studies, Original Investigation, Angiology, Type 1 diabetes, diabetes, business.industry, Incidence, Incidence (epidemiology), Diabetes, Hazard ratio, Age Factors, Atrial fibrillation, Middle Aged, medicine.disease, Confidence interval, sex-difference, 3. Good health, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, lcsh:RC666-701, Female, France, Cardiology and Cardiovascular Medicine, business |
| الوصف: | Background There remain uncertainties regarding diabetes mellitus and the incidence of atrial fibrillation (AF), in relation to type of diabetes, and the interactions with sex and age. We investigated whether diabetes confers higher relative rates of AF in women compared to men, and whether these sex-differences depend on type of diabetes and age. Methods All patients aged ≥ 18 seen in French hospitals in 2013 with at least 5 years of follow-up without a history of AF were identified and categorized by their diabetes status. We calculated overall and age-dependent incidence rates, hazard ratios, and women-to-men ratios for incidence of AF in patients with type 1 and type 2 diabetes (compared to no diabetes). Results In 2,921,407 patients with no history of AF (55% women), 45,389 had prevalent type 1 diabetes and 345,499 had prevalent type 2 diabetes. The incidence rates (IRs) of AF were higher in type 1 or type 2 diabetic patients than in non-diabetics, and increased with advancing age. Among individuals with diabetes, the absolute rate of AF was higher in men than in women. When comparing individuals with and without diabetes, women had a higher adjusted hazard ratio (HR) of AF than men: adjusted HR 1.32 (95% confidence interval 1.27–1.37) in women vs. 1.12(1.08–1.16) in men for type 1 diabetes, adjusted HR 1.17(1.16–1.19) in women vs. 1.10(1.09–1.12) in men for type 2 diabetes. Conclusion Although men have higher absolute rates for incidence of AF, the relative rates of incident AF associated with diabetes are higher in women than in men for both type 1 and type 2 diabetes. |
| وصف الملف: | application/pdf |
| تدمد: | 1475-2840 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::283960264e903fd4358fe6198494884eTest https://doi.org/10.1186/s12933-021-01216-7Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....283960264e903fd4358fe6198494884e |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14752840 |
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