Value of routine ultrasound examination at 35–37 weeks' gestation in diagnosis of fetal abnormalities
| العنوان: | Value of routine ultrasound examination at 35–37 weeks' gestation in diagnosis of fetal abnormalities |
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| المؤلفون: | A. Ficara, K. H. Nicolaides, A. Hammami, Argyro Syngelaki, Ranjit Akolekar |
| المصدر: | Ultrasound in Obstetrics & Gynecology. 55:75-80 |
| بيانات النشر: | Wiley, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | medicine.medical_specialty, Pregnancy Trimester, Third, Prenatal diagnosis, Ultrasonography, Prenatal, Dacryocystocele, 03 medical and health sciences, 0302 clinical medicine, Pregnancy, Third trimester screening, medicine, Humans, Abnormalities, Multiple, Radiology, Nuclear Medicine and imaging, Cyst, Prospective Studies, 030212 general & internal medicine, Pelvic kidney, 030219 obstetrics & reproductive medicine, Ovarian cyst, Radiological and Ultrasound Technology, Diagnostic Tests, Routine, business.industry, Obstetrics, Gastroschisis, Obstetrics and Gynecology, Congenital pulmonary airway malformation, General Medicine, medicine.disease, Reproductive Medicine, Fetal abnormalities, Ultrasound examination, Female, Pregnancy Trimesters, business, Ventriculomegaly |
| الوصف: | Objective To investigate the potential value of routine ultrasound examination at 35-37 weeks' gestation in the diagnosis of previously unknown fetal abnormalities. Methods This was a prospective study of 52 400 singleton pregnancies attending for a routine ultrasound examination at 35 + 0 to 36 + 6 weeks' gestation; all pregnancies had a previous scan at 18-24 weeks and 47 214 also had a scan at 11-13 weeks. We included pregnancies resulting in live birth or stillbirth but excluded those with known chromosomal abnormality. Abnormalities were classified according to the affected major organ system, and the type and incidence of new abnormalities were determined. Results In the study population, the incidence of fetal abnormality was 1.9% (995/52 400), including 674 (67.7%) that had been diagnosed previously during the first and/or second trimester, 247 (24.8%) that were detected for the first time at 35-37 weeks and 74 (7.4%) that were detected for the first time postnatally. The most common abnormalities that were diagnosed during the first and/or second trimester and that were also observed at 35-37 weeks included ventricular septal defect, talipes, unilateral renal agenesis and/or pelvic kidney, hydronephrosis, duplex kidney, unilateral multicystic kidney, congenital pulmonary airway malformation, ventriculomegaly, cleft lip and palate, polydactyly and abdominal cyst or gastroschisis. The most common abnormalities first seen at 35-37 weeks were hydronephrosis, mild ventriculomegaly, ventricular septal defect, duplex kidney, ovarian cyst and arachnoid cyst. The incidence of abnormalities first seen at 35-37 weeks was 0.5% and those that were detected exclusively for the first time at this examination were ovarian cyst, microcephaly, achondroplasia, dacryocystocele and hematocolpos. The incidence of abnormalities first seen postnatally was 0.1% and the most common were isolated cleft palate, polydactyly or syndactyly and ambiguous genitalia or hypospadias; prenatal examination of the genitalia was not a compulsory part of the protocol. Conclusions A high proportion of fetal abnormalities are detected for the first time during a routine ultrasound examination at 35-37 weeks' gestation. Such diagnosis and subsequent management, including selection of timing and place for delivery and postnatal investigations, could potentially improve postnatal outcome. Copyright © 2019 ISUOG. Published by John Wiley & Sons Ltd. |
| تدمد: | 1469-0705 0960-7692 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::276eaec5aa475a2a93693bf741580658Test https://doi.org/10.1002/uog.20857Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....276eaec5aa475a2a93693bf741580658 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14690705 09607692 |
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