Figure S4 from Chimeric Antigen Receptor T Cell–Mediated Neurotoxicity in Nonhuman Primates
| العنوان: | Figure S4 from Chimeric Antigen Receptor T Cell–Mediated Neurotoxicity in Nonhuman Primates |
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| المؤلفون: | Michael C. Jensen, Leslie S. Kean, Rebecca Gardner, Stanley R. Riddell, Carolina Berger, Bruce R. Blazar, Hannah Brakke, Olivia Finney, Virginia Hoglund, Daniel J. Hunt, Scott N. Furlan, Hengqi Zheng, Alison Yu, Chris English, Audrey Baldessari, Luis Gonzalez-Cuyar, David Myerson, H. Denny Liggitt, Jessica M. Snyder, Cameron J. Turtle, Rafael Ponce, Victor Tkachev, Agne Taraseviciute |
| بيانات النشر: | American Association for Cancer Research (AACR), 2023. |
| سنة النشر: | 2023 |
| الوصف: | A, Immunofluorescence images for CD20 (green), CD3 (red) and DAPI (blue) in R.304 before (pre, day -7) and following CD20 CAR T cell transfer (day 7 (d7)), in lymph node (LN) and brain (day 8 (d8)) and in normal RM brain. B, H&E CSF cytospin (day 8, R.304) shows marked lymphocytosis following CD20 CAR T cell transfer. C, Fraction (%) of EGFRt+ or EGFRt- CD4 an CD8 T cells expressing ï�¡4 and ï�¢1 integrins, in the blood of normal RM controls (n = 5), on day 0, pre-CD20 CAR infusion (d0, n = 4) and on day 7 or 8 (peak CD20 CAR expansion, (d7/8, n = 4)), in the CSF (on day 8 (R.304); d8, n = 1) and in the brain (on day 8 (R.304); d8, n = 1 ). * P < 0.05. |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23022081fc6cd05edc106d3439eadb30Test https://doi.org/10.1158/2159-8290.22532950.v1Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....23022081fc6cd05edc106d3439eadb30 |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |