Sustained Attention Deficits in Adults With Juvenile-Onset Type 1 Diabetes Mellitus
| العنوان: | Sustained Attention Deficits in Adults With Juvenile-Onset Type 1 Diabetes Mellitus |
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| المؤلفون: | Yuzhuo Liu, Jing He, Jiang Zhu, Fansu Huang, Wenjing Zou, Zhiguang Zhou, Xiongzhao Zhu, Hongyu Du, Xia Li, Chuting Li, Yuting Xie, Fang Liu |
| المصدر: | Psychosomatic Medicine. 83:906-912 |
| بيانات النشر: | Ovid Technologies (Wolters Kluwer Health), 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Adult, Type 1 diabetes, medicine.medical_specialty, business.industry, Wechsler Adult Intelligence Scale, Disease, medicine.disease, Hypoglycemia, Psychiatry and Mental health, Cognition, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Internal medicine, Diabetes mellitus, medicine, Humans, Juvenile, Cognitive Dysfunction, Attention deficits, Age of onset, business, Applied Psychology, Depression (differential diagnoses) |
| الوصف: | Objective This study aimed to investigate whether patients with juvenile-onset type 1 diabetes mellitus (T1DM) have poorer sustained attention than their counterparts with adult-onset T1DM, and whether there is a relationship between diabetes-related variables and sustained attention. Methods This study included 76, 68, and 85 participants with juvenile-onset and adult-onset T1DM, and healthy controls (HCs), respectively. All participants completed the Sustained Attention to Response Task, Beck Depression Inventory-II, and the Chinese version of the Wechsler Adult Intelligence Scale. Results The juvenile-onset group showed more omission errors (p = .007) than the adult-onset group and shorter reaction time (p = .005) than HCs, while the adult-onset group showed no significant differences compared with HCs. Hierarchical linear regression analysis revealed that the age of onset was associated with omission errors in T1DM participants (β = -0.275, t = -2.002, p = .047). In the juvenile-onset group, the omission error rate were associated with the history of severe hypoglycemia (β = 0.225, t = 1.996, p = .050), while reaction time was associated with the age of onset (β = -0.251, t = -2.271, p = .026). Fasting blood glucose levels were significantly associated with reaction time in both the juvenile-onset and adult-onset groups (β = -0.236, t = -2.117, p = .038 and β = 0.259, t = 2.041, p = .046, respectively). Conclusion Adults with juvenile-onset T1DM have sustained attention deficits, in contrast to their adult-onset counterparts, suggesting that the disease adversely affects the developing brain. Both the history of severe hypoglycemia and fasting blood glucose levels are factors associated with sustained attention impairment. Early diagnosis and treatment in juvenile patients are required to prevent the detrimental effects of diabetes. |
| تدمد: | 1534-7796 0033-3174 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21558dae09fc80439cae10046373827bTest https://doi.org/10.1097/psy.0000000000000992Test |
| رقم الانضمام: | edsair.doi.dedup.....21558dae09fc80439cae10046373827b |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15347796 00333174 |
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