Risky emotional family environment in childhood and depression‐related cytokines in adulthood: The protective role of compassion
| العنوان: | Risky emotional family environment in childhood and depression‐related cytokines in adulthood: The protective role of compassion |
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| المؤلفون: | Ari Ahola-Olli, Henrik Dobewall, Marko Salmi, Mirka Hintsanen, Terho Lehtimäki, Olli T. Raitakari, Liisa Keltikangas-Järvinen, Sirpa Jalkanen, Aino Saarinen |
| المساهمون: | Department of Psychology and Logopedics, Medicum, Institute for Molecular Medicine Finland, Genomics of Neurological and Neuropsychiatric Disorders |
| المصدر: | Developmental Psychobiology. 63:1190-1201 |
| بيانات النشر: | Wiley, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Adult, SELF-COMPASSION, STRESS, SYMPTOMS, 515 Psychology, media_common.quotation_subject, Emotions, Population, family environment, Compassion, PREDICT, 03 medical and health sciences, Behavioral Neuroscience, 0302 clinical medicine, INFLAMMATION, MARKERS, Developmental Neuroscience, ADVERSITY, Developmental and Educational Psychology, Humans, Personality, 0501 psychology and cognitive sciences, Prospective Studies, Emotional environment, education, Socioeconomic status, METAANALYSIS, POPULATION, Depressive symptoms, Depression (differential diagnoses), media_common, education.field_of_study, Depression, Tumor Necrosis Factor-alpha, CARDIOVASCULAR RISK, 05 social sciences, childhood environment, emotional environment, cytokines, personality, Empathy, Psychology, 030217 neurology & neurosurgery, Self-compassion, 050104 developmental & child psychology, Developmental Biology, Clinical psychology |
| الوصف: | Background: Previously, compassion has been found to protect against depressive symptoms, while emotional adversities in childhood are suggested to increase inflammatory responses. The current study investigated (a) whether emotional family environment in childhood predicts levels of such cytokines in adulthood that are previously found to be elevated in depression (interleukin [IL]-2, IL-6, IL-1b, monocyte chemoattractant protein-1, interferon-gamma [IFN-gamma], and tumor necrosis factor alpha [TNF-alpha]) and (b) whether these associations are modified by compassion in adulthood. Methods: The participants (N = 1,198-1,523) came from the prospective population-based Young Finns data. Emotional family environment and parental socioeconomic factors were evaluated in 1980; participants' compassion in 2001; and participants' cytokine levels and adulthood covariates in 2007. Results: Risky emotional family environment in childhood predicted higher levels of IL-2, IL-6, IFN-gamma, and TNF-alpha in adulthood. Additionally, there were significant interaction effects between compassion and emotional risk in childhood, when predicting IL-2, IL-6, and TNF-alpha. Specifically, individuals who grew up in a risky emotional family environment had on average higher levels of IL-2, IL-6, and TNF-alpha in adulthood when combined with low compassion. Conclusions: In individuals coming from risky emotional family environments, high compassion for others may protect against elevated levels of cytokines previously linked with depression. |
| تدمد: | 1098-2302 0012-1630 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20a3c32aab3971bed8b7aea59a727fa1Test https://doi.org/10.1002/dev.22070Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....20a3c32aab3971bed8b7aea59a727fa1 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 10982302 00121630 |
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