Dietary sodium intake is associated with long-term risk of new-onset atrial fibrillation
| العنوان: | Dietary sodium intake is associated with long-term risk of new-onset atrial fibrillation |
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| المؤلفون: | Heikki V. Huikuri, Tero J W Pääkkö, Juha S. Perkiömäki, Olavi Ukkola, Risto Bloigu, Marja-Leena Silaste, Y. Antero Kesäniemi |
| المصدر: | Annals of Medicine. 50:694-703 |
| بيانات النشر: | Informa UK Limited, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Adult, Male, Physiology, Blood Pressure, 030204 cardiovascular system & hematology, Body Mass Index, 03 medical and health sciences, 0302 clinical medicine, Risk Factors, Atrial Fibrillation, medicine, Humans, 030212 general & internal medicine, Antihypertensive Agents, business.industry, Incidence, Incidence (epidemiology), Smoking, Age Factors, Dietary sodium intake, Sodium, Dietary, Atrial fibrillation, Cholesterol, LDL, General Medicine, Middle Aged, medicine.disease, New onset atrial fibrillation, Sodium intake, Long term risk, Hypertension, Dietary salt intake, Female, business, Follow-Up Studies |
| الوصف: | The association between dietary salt intake and hypertension has been well documented. We evaluated the association between dietary sodium intake and the incidence of new-onset atrial fibrillation (AF) during a mean follow-up of 19 years among 716 subjects from the Oulu Project Elucidating Risk of Atherosclerosis (OPERA) cohort.Dietary sodium intake was evaluated from a seven-day food record. The diagnosis of AF (atrial flutter included) was made if ICD-10 code I48 was listed in the hospital discharge records during follow-up.In the Kaplan-Meier curves, when quartiles of sodium consumption were considered, the cumulative proportional probabilities for AF events were higher in the highest (4th) quartile (16.8%) than in the lower quartiles (1st 6.7%, 2nd 7.3% and 3rd 10.6%) (p = .003). In the Cox regression analysis, sodium consumption (g/1000 kcal) as a continuous variable was independently associated with AF events (Hazard Ratio = 2.1 (95% CI, 1.2 to 3.7) p =.015) when age, body mass index, smoking (pack-years), office systolic blood pressure, left atrium diameter, left ventricular mass index and the use of any antihypertensive therapy were added as covariates.These findings indicate that sodium intake is associated with the long-term risk of new-onset AF. Further confirmatory studies are needed. Key messages Sodium consumption correlated positively with CV risk factors: age, smoking, SBP, BMI and LDL-cholesterol. When quartiles of sodium consumption were considered, the AF incidence was higher in the highest quartile compared to lower quartiles. Sodium consumption as a continuous variable was independently associated with AF events when age, BMI, smoking, SBP, LAD, LVMI and the use of any antihypertensive therapy were considered. |
| تدمد: | 1365-2060 0785-3890 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fb4be4de334510c0c24d66135b0ff1aTest https://doi.org/10.1080/07853890.2018.1546054Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....1fb4be4de334510c0c24d66135b0ff1a |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 13652060 07853890 |
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