Autonomic and affective mediators of the relationship between mindfulness and opioid craving among chronic pain patients
| العنوان: | Autonomic and affective mediators of the relationship between mindfulness and opioid craving among chronic pain patients |
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| المؤلفون: | Anne K. Baker, Eric L. Garland |
| المصدر: | Experimental and Clinical Psychopharmacology. 27:55-63 |
| بيانات النشر: | American Psychological Association (APA), 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Adult, Male, Mindfulness, Protective factor, 030508 substance abuse, Craving, Article, Self-Control, 03 medical and health sciences, Heart Rate, Adaptation, Psychological, mental disorders, Heart rate, medicine, Humans, Pharmacology (medical), Pharmacology, Depression, business.industry, Chronic pain, Middle Aged, Opioid-Related Disorders, medicine.disease, Adaptation, Physiological, Analgesics, Opioid, Psychiatry and Mental health, Distress, Autonomic nervous system, Opioid, Female, Chronic Pain, Cues, medicine.symptom, 0305 other medical science, business, Clinical psychology, medicine.drug |
| الوصف: | Prescription opioid misuse among chronic pain patients is undergirded by self-regulatory deficits, affective distress, and opioid-cue reactivity. Dispositional mindfulness has been associated with enhanced self-regulation, lower distress, and adaptive autonomic responses following drug-cue exposure. We hypothesized that dispositional mindfulness might serve as a protective factor among opioid-treated chronic pain patients. We examined heart-rate variability (HRV) during exposure to opioid cues and depressed mood as mediators of the association between dispositional mindfulness and opioid craving. Data were obtained from a sample of chronic pain patients (N = 115) receiving long-term opioid pharmacotherapy. Participants self-reported opioid craving and depression, and HRV was measured during an opioid-cue dot-probe task. Dispositional mindfulness was significantly positively correlated with HRV, and HRV was significantly inversely associated with opioid craving. Dispositional mindfulness was significantly negatively correlated with depression, and depression was significantly positively correlated with opioid craving. Path analysis revealed significant indirect effects of dispositional mindfulness on craving through both HRV and depression. Dispositional mindfulness may buffer against opioid craving among chronic pain patients prescribed opioids; this buffering effect may be a function of improved autonomic and affective responses. (PsycINFO Database Record (c) 2019 APA, all rights reserved). |
| تدمد: | 1936-2293 1064-1297 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1db1121a0996076d1f84a836c142a17bTest https://doi.org/10.1037/pha0000225Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....1db1121a0996076d1f84a836c142a17b |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19362293 10641297 |
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