Higher lipoprotein (a) levels in atherothrombotic than lacunar ischemic cerebrovascular disease
| العنوان: | Higher lipoprotein (a) levels in atherothrombotic than lacunar ischemic cerebrovascular disease |
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| المؤلفون: | Graziella Bruno, Maurizio Cassader, P. Maffeis, Daniele Imperiale, Bruno Bergamasco, Gianfranco Pagano, P Cavallo Perin, Paolo Fornengo, Paolo Cerrato |
| المصدر: | Scopus-Elsevier |
| بيانات النشر: | Ovid Technologies (Wolters Kluwer Health), 2002. |
| سنة النشر: | 2002 |
| مصطلحات موضوعية: | Adult, Brain Infarction, Male, medicine.medical_specialty, Lacunar stroke, medicine.medical_treatment, Arteriolosclerosis, Brain Ischemia, Cohort Studies, Atheromatosis, Internal medicine, Fibrinolysis, medicine, Humans, cardiovascular diseases, Aged, Aged, 80 and over, biology, business.industry, Cerebral infarction, Lipoprotein(a), Middle Aged, medicine.disease, Thrombosis, Logistic Models, Intracranial Thrombosis, Endocrinology, biology.protein, Cardiology, Female, lipids (amino acids, peptides, and proteins), Neurology (clinical), business |
| الوصف: | To investigate the role of plasma lipid abnormalities in ischemic cerebrovascular disease related to primary vessel disease, the authors assess lipid profiles in a hospital-based cohort of 202 consecutive patients with atherothrombotic or lacunar stroke subtypes. Lipoprotein (a) was the unique lipid parameter that differs between these two subtypes being its value twofold higher in patients with atherothrombotic than in lacunar stroke. This suggests that lipoprotein (a) promotes large vessel atheromatosis rather than small vessel arteriolosclerosis and favors thrombosis on atheromatous plaques by suppressing local fibrinolysis. |
| تدمد: | 1526-632X 0028-3878 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19bb82397e3936566b95c0ab9c510e7bTest https://doi.org/10.1212/wnl.58.4.653Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....19bb82397e3936566b95c0ab9c510e7b |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1526632X 00283878 |
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